Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2021; 13(10): 1110-1121
Published online Oct 27, 2021. doi: 10.4240/wjgs.v13.i10.1110
Long-term survival outcome of laparoscopic liver resection for hepatocellular carcinoma
Shi Lam, Kai-Chi Cheng
Shi Lam, Kai-Chi Cheng, Department of Surgery, Kwong Wah Hospital, Hong Kong, 999077, China
Author contributions: Cheng KC designed the research study; Lam S analyzed the data and wrote the manuscript; and all authors have read and approved the final manuscript.
Conflict-of-interest statement: There are no conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
Corresponding author: Kai-Chi Cheng, FRCS (Ed), Doctor, Department of Surgery, Kwong Wah Hospital, 25, Waterloo Road, Kowloon, Hong Kong, 999077, China.
Received: March 11, 2021
Peer-review started: March 11, 2021
First decision: June 14, 2021
Revised: June 14, 2021
Accepted: September 7, 2021
Article in press: September 7, 2021
Published online: October 27, 2021
Core Tip

Core Tip: Laparoscopic liver resection (LLR) resulted in better perioperative outcomes when compared with open liver resection. However, for long-term outcomes, the reported ranges of disease-free survival rate and overall survival rate at 5 years after LLR of hepatocellular carcinoma (HCC) can be as wide as 20%-64% and 47%-95%, respectively. This reflects the heterogeneity of clinical practice and outcome reporting. The purpose of this review is to elucidate the true picture of the oncological efficacy of LLR in the treatment of HCC by critical appraisal of current evidence including meta-analyses and comparative studies.