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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2020; 12(12): 549-554
Published online Dec 27, 2020. doi: 10.4240/wjgs.v12.i12.549
Published online Dec 27, 2020. doi: 10.4240/wjgs.v12.i12.549
Giant simple hepatic cyst with multiple elevated serum tumor markers: A case report
Jia-Wei Zhang, Cheng Peng, Yan-Shuo Ye, Wei Li, Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China
Jia-Wei Zhang, Department of Vascular Surgery, The First Hospital of China Medical University, Shenyang 110001, Liaoning Province, China
Cheng Peng, Department of Hepatobiliary-Pancreatic Surgery, The Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Author contributions: Zhang JW initially identified the case, collected and organized the medical records, and performed an intensive revision of the manuscript; Peng C primarily drafted the article, accomplished the actual writing, selected the references, and drafted the discussion; Ye YS also performed the revision of the manuscript; Li W contributed to the conceptual design, and carried out critical revision and finalization of the manuscript.
Supported by Nature Science Foundation of The Science and Technology Bureau of Jilin Province , No. Li 20190201227JC ; and The Innovation Capacity Building Fund of The Development and Reform Commission of Jilin Province , No. Li 2019C015 .
Informed consent statement: The patient provided informed written consent for the publication of this case report.
Conflict-of-interest statement: None.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei Li, MD, PhD, Professor, Surgeon, Department of Hepatobiliary-Pancreatic Surgery, China-Japan Union Hospital of Jilin University, No. 126 Xiantai Street, Changchun 130033, Jilin Province, China. weili888@jlu.edu.cn
Received: July 23, 2020
Peer-review started: July 23, 2020
First decision: October 6, 2020
Revised: October 16, 2020
Accepted: November 12, 2020
Article in press: November 12, 2020
Published online: December 27, 2020
Peer-review started: July 23, 2020
First decision: October 6, 2020
Revised: October 16, 2020
Accepted: November 12, 2020
Article in press: November 12, 2020
Published online: December 27, 2020
Core Tip
Core Tip: Simple hepatic cysts typically appear as asymptomatic benign tumors of the liver without elevation of any diagnostic serum biomarkers. However, over the years, a few cases of simple hepatic cysts with elevated tumor markers have been reported in the world. Here, we report a case of giant simple hepatic cyst with elevation of multiple serum cancer biomarkers, including protein induced by vitamin K absence-II, cancer antigen (CA) 12-5, and CA19-9.