Copyright
©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2019; 11(3): 126-142
Published online Mar 27, 2019. doi: 10.4240/wjgs.v11.i3.126
Published online Mar 27, 2019. doi: 10.4240/wjgs.v11.i3.126
Liver graft preservation methods during cold ischemia phase and normothermic machine perfusion
Konstantin Y Tchilikidi, Department of Surgery, Altai State Medical University, Barnaul 656031, Russia
Author contributions: Tchilikidi KY made this manuscript entirely himself.
Conflict-of-interest statement: No potential conflicts of interest. No financial support.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Konstantin Y Tchilikidi, MD, Assistant Professor, Lecturer, Surgeon, Department of Surgery, Altai State Medical University, Krasnoarneysky Avenue 131-10, Barnaul 656031, Russia. k.tchilikidi@aol.com
Telephone: +7-385-2627005 Fax: +7-385-2627005
Received: February 26, 2019
Peer-review started: February 27, 2019
First decision: March 19, 2019
Revised: March 21, 2019
Accepted: March 24, 2019
Article in press: March 24, 2019
Published online: March 27, 2019
Peer-review started: February 27, 2019
First decision: March 19, 2019
Revised: March 21, 2019
Accepted: March 24, 2019
Article in press: March 24, 2019
Published online: March 27, 2019
Core Tip
Core tip: This review estimates the place of static cold storage, hypothermic and normothermic machine perfusion among liver graft preservation techniques. Regular grafts donated after brain death could be safely preserved with convenient static cold storage. Except for prolonged cold ischemia time where hypothermic machine perfusion started in transplant center could be estimated to provide possible positive reconditioning effect. Use of hypothermic machine perfusion in regular donation instead of static cold storage or in extended criteria donors requires further investigation. Normothermic machine perfusion is actively evaluating promising method for extended criteria donor grafts. Future studies are necessary.