Clinical Trials Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Mar 27, 2024; 16(3): 816-822
Published online Mar 27, 2024. doi: 10.4240/wjgs.v16.i3.816
Clinical study of enhanced recovery after surgery in laparoscopic appendectomy for acute appendicitis
Zhu-Lin Li, Hua-Chong Ma, Yong Yang, Jian-Jun Chen, Zhen-Jun Wang
Zhu-Lin Li, Hua-Chong Ma, Yong Yang, Jian-Jun Chen, Zhen-Jun Wang, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China
Author contributions: Li ZL, Wang ZJ and Ma HC designed the study; Li ZL and Chen JJ collected and analyzed the data; Li ZL wrote the manuscript; Yang Y and Ma HC revised the manuscript; Yang Y participated in collection of the data; All authors approved the final version of the manuscript.
Institutional review board statement: The study was reviewed and approved by the Beijing Chao-Yang Hospital’s Ethics and Medical Committee (approval No. 2018-Ke-340).
Clinical trial registration statement: This study is registered at https://www.chictr.org.cn/searchproj.html; The registration identification number is ChiCTR2400081069.
Informed consent statement: Informed consent was obtained from all patients and their families.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No additional data are available.
CONSORT 2010 statement: The authors have read the CONSORT 2010 statement, and the manuscript was prepared and revised according to the CONSORT 2010 statement.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Zhen-Jun Wang, MD, Chief Physician, Director, Department of General Surgery, Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Gongtinan Road, Chaoyang District, Beijing 100020, China. drzhenjun@163.com
Received: January 12, 2024
Peer-review started: January 12, 2024
First decision: January 31, 2024
Revised: February 9, 2024
Accepted: February 25, 2024
Article in press: February 25, 2024
Published online: March 27, 2024
Processing time: 70 Days and 7.3 Hours
ARTICLE HIGHLIGHTS
Research background

Enhanced recovery after surgery (ERAS) protocol has shown to be beneficial to patients undergoing various abdominal surgeries, especially in the digestive tumor surgery. However, few studies have explored the application of ERAS in laparoscopic surgery for acute appendicitis.

Research motivation

To determine if ERAS is beneficial to patients undergoing laparoscopic surgery for acute appendicitis.

Research objectives

This study aimed to evaluate the value of ERAS in laparoscopic surgery for acute appendicitis.

Research methods

A prospective randomized controlled study was performed in Beijing Chao-Yang Hospital. A total of 120 patients who met the inclusion criteria and were diagnosed with acute appendicitis before surgery between March 2018 and March 2020 were randomly divided into an experimental group and a control group using a random number table method. The clinicopathological features of the two groups were analyzed. In addition, variables including gastrointestinal function recovery time, hospitalization duration, hospitalization costs, and pain scores were also analyzed.

Research results

One hundred and twenty patients were included. There were 63 patients in the experimental group and 57 patients in the control group. There was no significant difference in age, gender, body mass index and Sunshine Appendicitis Grading System score between the two groups (P > 0.05). The application of ERAS resulted in accelerated recovery of acute appendicitis patients, shorter hospitalization stay, less hospitalization costs, earlier postoperative exhaust time, and milder pain.

Research conclusions

The application of ERAS is associated with shorter hospitalization stay, less hospitalization costs, earlier postoperative exhaust time, and milder pain in the patients who underwent laparoscopic appendectomy due to acute appendicitis. It is safe, economical and effective.

Research perspectives

The findings in this study can encourage surgeons to pay more attention to postoperative management measures for patients with acute appendicitis, and to apply the concept of ERAS to their postoperative recovery, thereby reducing the burden on patients and saving medical resources.