Retrospective Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2024; 16(1): 124-133
Published online Jan 27, 2024. doi: 10.4240/wjgs.v16.i1.124
Clinical effect of laparoscopic radical resection of colorectal cancer based on propensity score matching
Yang Liu, Xian-Xue Wang, Yu-Lin Li, Wen-Tao He, Hong Li, Hua Chen
Yang Liu, Yu-Lin Li, Wen-Tao He, Hong Li, Hua Chen, Department of General Surgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415000, Hunan Province, China
Xian-Xue Wang, Department of Anesthesiology, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), Changde 415000, Hunan Province, China
Author contributions: Liu Y designed and performed the research and wrote the paper; Chen H designed the research and supervised the report; Wang XX and Li H designed the research and organized the data; Li YL and He WT designed the research and contributed to the analysis. All authors approved the manuscript.
Supported by Scientific Research Project of Hunan Provincial Health Commission, No. 202204114103.
Institutional review board statement: The study was reviewed and approved by the Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City) Institutional Review Board, Approval No. 2021-265-02.
Informed consent statement: All patients have signed informed consent forms.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The clinical data used in this study can be obtained from the corresponding author upon request at 229chenhua@sina.com.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hua Chen, MD, Associate Professor, Department of General Surgery, Changde Hospital, Xiangya School of Medicine, Central South University (The First People’s Hospital of Changde City), No. 388 Renming Road, Changde 415000, Hunan Province, China. 229chenhua@sina.com
Received: November 21, 2023
Peer-review started: November 21, 2023
First decision: December 5, 2023
Revised: December 16, 2023
Accepted: December 28, 2023
Article in press: December 28, 2023
Published online: January 27, 2024
ARTICLE HIGHLIGHTS
Research background

Currently, there is some debate about the merits of laparoscopic surgery of colorectal cancer (CRC).

Research motivation

The advantages of laparoscopic surgery for CRC require further validation through additional studies and data.

Research objectives

Exploring the advantages of laparoscopic radical resection vs open surgery for CRC.

Research methods

Data from 43 patients with CRC who underwent open surgery and 53 who underwent laparoscopic surgery were compared retrospectively, and differences between the groups were analyzed using 1:1 propensity score matching equilibrium treatment.

Research results

Compared with open surgery, laparoscopic radical resection of CRC showed better early inflammatory, immune, and pain indicators, and better physical status one month after surgery.

Research conclusions

Laparoscopic radical resection of CRC can reduce postoperative pain and postoperative inflammatory responses, prevent excessive immune inhibition, and contribute to postoperative recovery.

Research perspectives

To analyze the early clinical effects of laparoscopic radical resection for CRC.