Retrospective Study
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Sep 27, 2023; 15(9): 1950-1958
Published online Sep 27, 2023. doi: 10.4240/wjgs.v15.i9.1950
Efficacy of ileus tube combined with meglumine diatrizoate in treating postoperative inflammatory bowel obstruction after surgery
Wen Yang, Jing Pu
Wen Yang, Jing Pu, Department of Third General Surgery, Lanzhou Second People’s Hospital, Lanzhou 730046, Gansu Province, China
Author contributions: Yang W initiated the project, designed the experiment, performed postoperative follow-up and recorded data, and wrote the original manuscript; Pu J conducted collated data, assisted with the statistical analysis, and revised the paper; all authors reviewed and approved the paper; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of Lanzhou Second People’s Hospital.
Informed consent statement: Due to the retrospective design, patient consent was not required.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study are included in this published article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jing Pu, MD, Doctor, Department of Third General Surgery, Lanzhou Second People’s Hospital, No. 388 Jingyuan Road, Lanzhou 730046, Gansu Province, China. 18119373828@163.com
Received: May 21, 2023
Peer-review started: May 21, 2023
First decision: June 1, 2023
Revised: July 3, 2023
Accepted: July 29, 2023
Article in press: July 29, 2023
Published online: September 27, 2023
ARTICLE HIGHLIGHTS
Research background

Early postoperative inflammatory small bowel obstruction (EPISBO) is easy to be complicated after colorectal cancer surgery. Both intestinal obstruction catheter and meglumine can treat EPISBO. Extensive application of parenteral nutrition support, traditional nasogastric tube, intestinal obstruction catheter and meglumine in EPISBO treatment. Research significance is to explore a new method for the treatment of EPISBO after colorectal cancer surgery.

Research motivation

The main topics is treatment of EPISBO after colorectal cancer surgery. There is a clinical need to explore more effective therapies to treat EPISBO after colorectal cancer surgery. The significance of this study is to confirm the effectiveness of the new method of ileus catheter combined with meglumine for the treatment of EPISBO after colorectal cancer surgery, encourage clinical teams to continue to explore more effective treatment methods for EPISBO after colorectal cancer surgery, and promote the continuous progress of medical technology.

Research objectives

To compare the effects of different treatment methods for EPISBO, and to observe the advantages of intestinal obstruction catheter combined with meglumine in the treatment of EPISBO. The combination of intestinal obstruction catheter and meglumine in the treatment of EPISBO after colorectal cancer surgery can significantly improve the short-term prognosis, inflammatory status and nutritional status of patients, which confirms that this treatment method has a good therapeutic effect, and provide a new reference for future clinical treatment of EPISBO after colorectal cancer surgery.

Research methods

Clinical data of patients were retrospectively analyzed and divided into three groups according to different treatment methods. One-way analysis of variance, paired sample t-test and Chi-square test were used to statistically analyze the general data, clinical efficacy, short-term prognostic indicators, inflammatory factors, nutritional status indicators and incidence of adverse reactions of patients in the three groups. The feature of retrospective study is to explore the cause through the results, and it is easier to obtain the case data.

Research results

Intestinal obstruction catheter combined with meglumine has a significant effect in the treatment of EPISBO after colorectal cancer surgery, showing good improvement in clinical efficacy, short-term prognosis, inflammatory status and nutritional status, providing a new treatment method for EPISBO after colorectal cancer surgery, and further prospective studies are needed to verify the effectiveness of this treatment method.

Research conclusions

Malnutrition in EPISBO patients can lead to a variety of complications and affect the prognosis of patients. Therefore, attention should be paid to the influence of treatment methods on the nutritional status of patients after treatment. Intestinal obstruction catheter combined with meglumine is effective in the treatment of EPISBO after colorectal cancer surgery, and the clinical treatment plan with better effect should be preferred.

Research perspectives

Clinical treatment plan should not only consider the therapeutic effect, but also consider the impact on the patient’s prognosis. Future research is aimed at further exploring the impact of medicine on quality of life.