Wang J, Li MH. Risk factors for anastomotic fistula development after radical colon cancer surgery and their impact on prognosis. World J Gastrointest Surg 2023; 15(11): 2470-2481 [PMID: 38111776 DOI: 10.4240/wjgs.v15.i11.2470]
Corresponding Author of This Article
Min-Hua Li, RN, Associate Chief Nurse, Department of Gastroenterology, The Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. huqingtongzhi@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Nov 27, 2023; 15(11): 2470-2481 Published online Nov 27, 2023. doi: 10.4240/wjgs.v15.i11.2470
Risk factors for anastomotic fistula development after radical colon cancer surgery and their impact on prognosis
Jun Wang, Min-Hua Li
Jun Wang, Department of Gastrointestinal Surgery, The Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Min-Hua Li, Department of Gastroenterology, The Affiliated Hospital of Jiangnan University, Wuxi 214000, Jiangsu Province, China
Author contributions: Wang J designed the study; Li MH contributed to the analysis of the manuscript; all authors were involved in the data collection and writing of this article; and all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board at the Affiliated Hospital of Jiangnan University.
Informed consent statement: The authors take full responsibility for the accuracy and integrity of the work. The study was conducted in accordance with the Declaration of Helsinki (as revised in 2013), and informed consent was obtained from all patients.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Min-Hua Li, RN, Associate Chief Nurse, Department of Gastroenterology, The Affiliated Hospital of Jiangnan University, No. 1000 Hefeng Road, Binhu District, Wuxi 214000, Jiangsu Province, China. huqingtongzhi@163.com
Received: August 15, 2023 Peer-review started: August 15, 2023 First decision: August 31, 2023 Revised: September 5, 2023 Accepted: October 23, 2023 Article in press: October 23, 2023 Published online: November 27, 2023 Processing time: 104 Days and 0.2 Hours
ARTICLE HIGHLIGHTS
Research background
Patients are prone to complications such as anastomotic fistula after radical colon cancer surgery.
Research motivation
Postoperative complications such as anastomotic fistulas have a significant negative impact on patient prognosis.
Research objectives
This study aimed to investigate the risk factors for postoperative anastomotic fistulas and their impact on the prognosis of patients with colon cancer.
Research methods
This retrospective analysis of 488 patients with colon cancer who underwent radical surgery between April 2016 and April 2019 at our research center was summarized, and the risk factors for the development of anastomotic fistula and the impact of anastomotic fistula occurrence on patient prognosis were analyzed.
Research results
A total of 38 (7.8%) of 488 patients who underwent radical surgery for colon cancer had complications of postoperative anastomotic fistula with a mean Functional Assessment of Cancer Therapy-Colorectal score of 74.79 ± 11.86.
Research conclusions
Based on the results of our study, we present the independent risk factors affecting the development of anastomotic fistulas and the prognosis of patients with colon cancer after radical surgery. The main causes and preventive measures are also described.
Research perspectives
Based on the clinical data comparing patients who developed anastomotic fistulas with those who did not, the factors influencing the development of anastomotic fistulas in patients postoperatively were analyzed, and the prognoses of the two groups of patients were compared.
