Zhang XJ, Fei H, Guo CG, Sun CY, Li ZF, Li Z, Chen YT, Che X, Zhao DB. Analysis of textbook outcomes for ampullary carcinoma patients following pancreaticoduodenectomy. World J Gastrointest Surg 2023; 15(10): 2259-2271 [PMID: 37969713 DOI: 10.4240/wjgs.v15.i10.2259]
Corresponding Author of This Article
Dong-Bing Zhao, MD, Doctor, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. dbzhao@cicams.ac.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Oct 27, 2023; 15(10): 2259-2271 Published online Oct 27, 2023. doi: 10.4240/wjgs.v15.i10.2259
Analysis of textbook outcomes for ampullary carcinoma patients following pancreaticoduodenectomy
Xiao-Jie Zhang, He Fei, Chun-Guang Guo, Chong-Yuan Sun, Ze-Feng Li, Zheng Li, Ying-Tai Chen, Xu Che, Dong-Bing Zhao
Xiao-Jie Zhang, He Fei, Chun-Guang Guo, Chong-Yuan Sun, Ze-Feng Li, Zheng Li, Ying-Tai Chen, Xu Che, Dong-Bing Zhao, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China
Xu Che, Department of Hepatobiliary and Pancreatic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital & Shenzhen Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Shenzhen, 518116, China
Author contributions: Zhang XJ, Fei H and Guo CG contributed equally to this work; Chen YT, Che X and Zhao DB designed the research study, they are the corresponding authors of this paper; Fei H and Zhang XJ analyzed the data; Sun CY, Li Z and Li ZF collected the data; All author wrote the manuscript; All authors have read and approve the final manuscript.
Institutional review board statement: Ethical review and approval were not required for this study in accordance with the National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: None of the authors have conflicts of interest related to the manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dong-Bing Zhao, MD, Doctor, Department of Pancreatic and Gastric Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, No. 17 Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. dbzhao@cicams.ac.cn
Received: July 11, 2023 Peer-review started: July 11, 2023 First decision: August 31, 2023 Revised: September 1, 2023 Accepted: September 7, 2023 Article in press: September 7, 2023 Published online: October 27, 2023 Processing time: 108 Days and 6.6 Hours
ARTICLE HIGHLIGHTS
Research background
Textbook outcome (TO) is a composite measure that represents the ideal outcome and has been used to assess the quality of surgical treatment in many digestive tumors.
Research motivation
Lack of an effective measure to evaluate the quality of surgery for ampullary carcinoma (AC).
Research objectives
This study aimed to investigate the impact of TO on survival for AC patients following pancreaticoduodenectomy and the factors associated with achieving TO.
Research methods
We defined the concept of TO in ampullary carcinoma and cox regression analysis was used to identify if TO was an independent prognostic factor for overall survival and recurrence free survival.
Research results
Only approximately a quarter (24.3%) of patients achieved TO and TO was independently related to favorable oncological outcomes in AC.
Research conclusions
TO was a simple and reliable composite measure of ideal outcomes following pancreaticoduodenectomy.
Research perspectives
Further multicenter research is warranted to better elucidate the impact of TO.
