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©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jan 27, 2023; 15(1): 72-81
Published online Jan 27, 2023. doi: 10.4240/wjgs.v15.i1.72
Published online Jan 27, 2023. doi: 10.4240/wjgs.v15.i1.72
Impact of body mass index in elderly patients treated with laparoscopic liver resection for hepatocellular carcinoma
Maria Conticchio, Antonella Delvecchio, Riccardo Memeo, Unit of Hepato-Pancreatic-Biliary Surgery, “F. Miulli” Regional General Hospital, Bari 70021, Italy
Riccardo Inchingolo, Interventional Radiology Unit, “F. Miulli” Regional General Hospital, Bari 70021, Italy
Francesca Ratti, Luca Antonio Aldrighetti, Unit of Hepatobiliary Surgery, San Raffaele Hospital, Milano 20132, Italy
Maximiliano Gelli, Departement de Chirurgie Viscérale, Gustave Roussy Cancer Campus Grand Paris, Paris 94800, France
Massimiliano Ferdinando Anelli, Javier Briceño, Unit of Oncologic and Pancreatic Surgery, Hospital University Reina Sofía, Cordoba 14004, Spain
Alexis Laurent, Nicola de’Angelis, Assistance Publique-Hôpitaux de Paris, Department of Digestive and Hepatobiliary Surgery, Centre Hospitalier Universitaire Henri Mondor, Créteil, Paris 94000, France
Giulio Cesare Vitali, Service of Abdominal Surgery, Poliambulanza Foundation, Brescia 25124, Italy
Paolo Magistri, Giacomo Assirati, Fabrizio di Benedetto, Hepato-Pancreato-Biliary Surgery and Liver Transplantation Unit, University of Modena and Reggio Emilia, Modena 41121, Italy
Emanuele Felli, Taiga Wakabayashi, Institut de Recherche Contre les Cancers de l’Appareil Digestif (IRCAD), Strasbourg 67000, France
Patrick Pessaux, Service de Chirurgie Viscérale et Digestive, Nouvel Hôpital Civil, Strasbourg 67000, France
Tullio Piardi, Department of Surgery, Hôpital Robert Debré, Reims 51092, France
Antonio Rampoldi, Interventional Radiology Unit, Niguarda Hospital, Milan 20162, Italy
Renè Adam, Daniel Cherqui, Department of Surgery, Centre Hepatobiliaire, Hopital Paul Brousse, Paris 94000, France
Author contributions: Conticchio M, Inchingolo R, Delvecchio A, Ratti F, Gelli M, Anelli MF, Laurent A, Vitali GC, Magistri P, Assirati G, Felli E, Wakabayashi T, Pessaux P, Piardi T, di Benedetto F, de’Angelis N, Briceño J, Rampoldi A, Adam R, Cherqui D, Aldrighetti LA, and Memeo R equally contributed to this paper with conception and design of the study, literature review and analysis, drafting and critical revision and editing, and final approval of the final version.
Institutional review board statement: This study didn’t require the approval by the Ethics Committee of the Azienda Ospedaliera Universitaria Policlinico of Bari, General Regional Hospital “F. Miulli”, Acquaviva delle Fonti (BA), San Raffaele Hospital of Milan, Gustave Roussy Cancer Campus Grand Paris of Paris, Hospital University Reina Sofía of Córdoba, Centre hospitalier universitaire Henri Mondor of Paris, Geneva University Hospitals and Medical School of Geneva, University of Modena and Reggio Emilia of Modena, Institut de Recherche Contre les Cancers de l’Appareil Digestif (IRCAD) of Strasbourg, Hôpital Robert Debré of Reims, Niguarda Hospital of Milan, Centre Hepatobiliaire, Hopital Paul Brousse, of Paris.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: All the authors are aware of the content of the manuscript and have no conflict of interest.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Riccardo Inchingolo, MD, Chief Doctor, Director, Interventional Radiology Unit, “F. Miulli” Regional General Hospital, Strada Prov 127 Acquaviva-Santeramo Km, 410070021 Acquaviva delle Fonti (BARI), Bari 70021, Italy. riccardoin@hotmail.it
Received: July 24, 2022
Peer-review started: July 24, 2022
First decision: September 19, 2022
Revised: October 14, 2022
Accepted: December 6, 2022
Article in press: December 6, 2022
Published online: January 27, 2023
Processing time: 178 Days and 0.4 Hours
Peer-review started: July 24, 2022
First decision: September 19, 2022
Revised: October 14, 2022
Accepted: December 6, 2022
Article in press: December 6, 2022
Published online: January 27, 2023
Processing time: 178 Days and 0.4 Hours
ARTICLE HIGHLIGHTS
Research background
A high body mass index (BMI) could represent a factor which impacts perioperative outcomes in elderly patients who underwent laparoscopic liver resection (LLR).
Research motivation
To evaluate of postoperative outcomes between elderly (age > 70 years) patients with a BMI ≥ 30 and BMI < 30 who underwent a LLR for hepatocellular carcinoma (HCC).
Research objectives
The analysis of short (perioperative) and long-term (oncological results) outcomes.
Research methods
The analysis of data was performed before and after propensity score matching.
Research results
After propensity score matching, patients in two groups presented comparable results, in terms of operative time complications rate length of hospital stay. There are no significant differences in terms of short- and long-term postoperative results.
Research conclusions
The present study showed that BMI did not impact perioperative and oncologic outcomes in elderly patients treated by laparoscopic resection for HCC.
Research perspectives
Randomized controlled studies are needed to better explore these results.