Correia de Sá T, Soares C, Rocha M. Acute pancreatitis and COVID-19: A literature review. World J Gastrointest Surg 2021; 13(6): 574-584 [PMID: 34194615 DOI: 10.4240/wjgs.v13.i6.574]
Corresponding Author of This Article
Tiago Correia de Sá, MD, Surgeon, Department of General Surgery, Centro Hospitalar do Tâmega e Sousa, Avenida do Hospital Padre Américo 210, Penafiel 4564-007, Portugal. tiago.rc.sa@gmail.com
Research Domain of This Article
Surgery
Article-Type of This Article
Systematic Reviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jun 27, 2021; 13(6): 574-584 Published online Jun 27, 2021. doi: 10.4240/wjgs.v13.i6.574
Acute pancreatitis and COVID-19: A literature review
Tiago Correia de Sá, Carlos Soares, Mónica Rocha
Tiago Correia de Sá, Carlos Soares, Mónica Rocha, Department of General Surgery, Centro Hospitalar do Tâmega e Sousa, Penafiel 4564-007, Portugal
Author contributions: Correia de Sá T, Soares C, and Rocha M designed the research study and performed the research; Correia de Sá T analyzed the data and wrote the manuscript; All authors have read, reviewed, and approved the final manuscript.
Conflict-of-interest statement: The authors declare no conflicts of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Tiago Correia de Sá, MD, Surgeon, Department of General Surgery, Centro Hospitalar do Tâmega e Sousa, Avenida do Hospital Padre Américo 210, Penafiel 4564-007, Portugal. tiago.rc.sa@gmail.com
Received: January 10, 2021 Peer-review started: January 10, 2021 First decision: February 14, 2021 Revised: February 26, 2021 Accepted: June 1, 2021 Article in press: June 1, 2021 Published online: June 27, 2021
ARTICLE HIGHLIGHTS
Research background
There is increasing literature connecting acute pancreatitis (AP) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but whether SARS-CoV-2 can cause AP or is an epiphenomenon remains a subject of debate.
Research motivation
To explore current literature and provide a concise overview of the current evidence as well as possible mechanisms of pancreatic injury in coronavirus disease 2019 (COVID-19) patients.
Research objectives
To provide an overview of current evidence on AP in COVID-19 patients and to promote and enhance future studies on this special subset of patients.
Research methods
Systematic and narrative review of the literature.
Research results
Available studies on AP in COVID-19 patients present important limitations and mechanisms of pancreatic injury are debatable and not completely understood.
Research conclusions
Currently there is insufficient evidence showing that SARS-CoV-2 infection can cause AP and the therapeutic and prognostic significance of AP in COVID-19 patients is largely unknown.
Research perspectives
This is a very important issue, requiring ongoing research.
