Published online May 27, 2021. doi: 10.4240/wjgs.v13.i5.419
Peer-review started: January 12, 2021
First decision: February 14, 2021
Revised: February 19, 2021
Accepted: April 26, 2021
Article in press: April 26, 2021
Published online: May 27, 2021
In recent years, a new anastomosis method, “bridging” pancreaticogastrostomy, to treat patients with an extremely severe pancreatic injury was created and employed. This surgery has advantages such as short length of surgery, low secondary trauma, rapid construction of shunts for pancreatic fluid, preventing second surgeries, and achieving good treatment outcomes in clinical practice.
There is a lack of strong evidence to support the feasibility and safety of this surgical procedure. We carried out an animal experiment to examine this procedure.
This study aimed to examine the feasibility and safety of a new rapid method of pancreaticogastrostomy, “bridging” pancreaticogastrostomy.
In total, 10 Landrace pigs were randomized into the experimental and control groups. “Bridging” pancreaticogastrostomy was performed in the experimental group, while routine mucosa-to-mucosa pancreaticogastrostomy was performed in the control group. The resurgery was carried out at 1 and 6 mo after the first surgery to examine the condition of the abdominal cavity and firmness and tightness of the pancreaticogastric anastomosis and pancreas.
One animal in the control group did not gain weight 6 mo after surgery, whereas significant weight gain was present in the others. There were significant differences on Days 1 and 3 after surgery between the two groups but no differences on Days 5 and 7. One month after surgery, the sinus tract orifice/anastomosis was patent in the two groups. Six months after surgery, the sinus tract orifice/anastomosis was sealed, and pancreases in both groups presented with chronic pancreatitis.
"Bridging" pancreaticogastrostomy is completely feasible as a means of damage control surgery during the early stage of pancreatic injury.
“Bridging” pancreaticogastrostomy can be used to establish rapidly a channel and has similar short- and long-term results as conventional pancreaticogastrostomy.