Klasen J, Güller U, Muff B, Candinas D, Seiler CA, Fahrner R. Treatment options for spontaneous and postoperative sclerosing mesenteritis. World J Gastrointest Surg 2016; 8(11): 761-765 [PMID: 27933138 DOI: 10.4240/wjgs.v8.i11.761]
Corresponding Author of This Article
René Fahrner, MD, Division of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, D-07740 Jena, Germany. rene.fahrner@med.uni-jena.de
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Nov 27, 2016; 8(11): 761-765 Published online Nov 27, 2016. doi: 10.4240/wjgs.v8.i11.761
Treatment options for spontaneous and postoperative sclerosing mesenteritis
Jennifer Klasen, Ulrich Güller, Brigitte Muff, Daniel Candinas, Christian A Seiler, René Fahrner
Jennifer Klasen, Department of Surgery, Kantonsspital Frauenfeld, Spital Thurgau AG, CH-8500 Frauenfeld, Switzerland
Ulrich Güller, Division of Medical Oncology and Hematology, Kantonsspital St. Gallen, CH-9007 St. Gallen, Switzerland
Brigitte Muff, Division of General Surgery, Spital Bülach, CH-8180 Bülach, Switzerland
Daniel Candinas, Christian A Seiler, Division of Visceral Surgery and Medicine, University Hospital Bern, CH-3010 Bern, Switzerland
René Fahrner, Division of General, Visceral and Vascular Surgery, University Hospital Jena, D-07740 Jena, Germany
Author contributions: Klasen J, Güller U, Muff B, Candinas D, Seiler CA and Fahrner R designed the review; Klasen J and Fahrner R performed the review and collection of data; Klasen J and Fahrner R wrote the paper; Güller U, Muff B, Candinas D and Seiler CA revised the paper.
Institutional review board statement: All data were analyzed according to the University of Bern Institutional Review Board guidelines and in strict adherence to the ethical guidelines for human research of the Swiss Academy of Medical Sciences.
Informed consent statement: All study participants, or their legal guardian, provided verbal informed consent.
Conflict-of-interest statement: All authors have no conflicts of interest or financial ties to disclose.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: René Fahrner, MD, Division of General, Visceral and Vascular Surgery, University Hospital Jena, Am Klinikum 1, D-07740 Jena, Germany. rene.fahrner@med.uni-jena.de
Telephone: +49-3641-9322686 Fax: +49-3641-9322602
Received: June 26, 2016 Peer-review started: June 26, 2016 First decision: August 5, 2016 Revised: August 19, 2016 Accepted: September 7, 2016 Article in press: September 8, 2016 Published online: November 27, 2016 Processing time: 149 Days and 17.9 Hours
Abstract
Sclerosing mesenteritis is a rare pathology with only a few described cases in the literature. The etiology is unclear; however, several potential triggers, including abdominal surgery and abdominal trauma, have been discussed. The pathology includes a benign acute or chronic inflammatory process affecting the adipose tissue of the mesenterium. Despite it being a rare disease, sclerosing mesenteritis is an important differential diagnosis in patients after abdominal surgery or patients presenting spontaneously with signs of acute inflammation and abdominal pain. We present here three cases with sclerosing mesenteritis. In two cases, sclerosing mesenteritis occurred postoperatively after abdominal surgery. One patient was treated because of abdominal pain and specific radiological signs revealing spontaneous manifestation of sclerosing mesenteritis. So far there are no distinct treatment algorithms, so the patients were treated differently, including steroids, antibiotics and watchful waiting. In addition, we reviewed the current literature on treatment options for this rare disease.
Core tip: Sclerosing mesenteritis is a rare pathology including a benign acute or chronic inflammatory process affecting the adipose tissue of the mesenterium. The etiology is unclear; however, several potential triggers, including abdominal surgery and abdominal trauma, have been discussed. So far there is no evidence in the treatment of these patients. But, in the case of a non-resolving bowel obstruction, surgery is needed.
