Review
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World J Gastrointest Surg. Nov 27, 2010; 2(11): 381-384
Published online Nov 27, 2010. doi: 10.4240/wjgs.v2.i11.381
An ongoing dispute in the management of severe pancreatic fistula: Pancreatospleenectomy or not?
Dionysios Dellaportas, Aliki Tympa, Constantinos Nastos, Vasiliki Psychogiou, Andreas Karakatsanis, Andreas Polydorou, George Fragulidis, Ioannis Vassiliou, Vassilios Smyrniotis
Dionysios Dellaportas, Constantinos Nastos, Vasiliki Psychogiou, Andreas Karakatsanis, Andreas Polydorou, George Fragulidis, Ioannis Vassiliou, Second Department of Surgery, Athens Medical School, Aretaieion Hospital, 76 Vassilisis Sofias Avenue, 11528 Athens, Greece
Aliki Tympa, Vassilios Smyrniotis, Fifth Department of Surgery, Athens Medical School, Aretaieion Hospital, 76 Vassilisis Sofias Avenue, 11528 Athens, Greece
Author contributions: Dellaportas D performed research and wrote the paper; Tympa A and Nastos C analyzed the data; Psychogiou V and Karakatsanis A designed the tables and structure of the article; Polydorou A, Fragulidis G and Vassiliou I revised the article; Smyrniotis V gave the final approval of the version to be published.
Correspondence to: Dionysios Dellaportas, MD, Second Department of Surgery, Athens Medical School, Aretaieio Hospital, 76 Vassilissis Sofias Ave., 11528 Athens, Greece. dellapdio@gmail.com
Telephone: +30-210-1004177 Fax: +30-210-7286128
Received: June 1, 2010
Revised: September 18, 2010
Accepted: September 26, 2010
Published online: November 27, 2010
Abstract

The aim of this manuscript is to review controversies in managing severe pancreatic fistula after pancreatic surgery. Significant progress in surgical technique and perioperative care has reduced the mortality rate of pancreatic surgery. However, leakage of the pancreatic stump still accounts for the majority of surgical complications after pancreatic resection. Various strategies have been employed in order to manage pancreatic fistula. Nonetheless high grade pancreatic fistula evokes controversy in relation to the choice of treatment. A Medline search was performed, with regard to conservative treatment options versus completion pancreatectomy for the management of pancreatic fistula grade C. Pancreatic fistula rates remain unchanged with an incidence ranging from 5%-20% and this is considered as the most important cause of postoperative death. Many authors claim that completion pancreatectomy has probably lost its role in favour of interventional radiology procedures, while others believe that completion pancreatectomy continues to have a place in the management of patients with severe clinical deterioration after pancreatic fistula who do not respond to non-surgical interventions. There is no agreement on the best clinical management of severe pancreatic fistula after pancreatic surgery. Completion pancreatectomy is reserved for patients not improving with conventional measures.

Keywords: Pancreatic fistula; Pancreatoduodenectomy; Pancreatospleenectomy; Completion pancreatectomy; Percutaneous drainage