Huang XR, Zhu DS, Yu YH. Surgical resection for simultaneous intraductal papillary mucinous neoplasm of the bile duct and pancreatic duct: A case report. World J Gastrointest Surg 2025; 17(8): 108767 [DOI: 10.4240/wjgs.v17.i8.108767]
Corresponding Author of This Article
Ya-Hong Yu, MD, Chief Physician, FRCS (Gen Surg), Professor, Department of Biliopancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jie Fang Avenue, Wuhan 430000, Hubei Province, China. yuyahong615@sina.com
Research Domain of This Article
Surgery
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Aug 27, 2025; 17(8): 108767 Published online Aug 27, 2025. doi: 10.4240/wjgs.v17.i8.108767
Surgical resection for simultaneous intraductal papillary mucinous neoplasm of the bile duct and pancreatic duct: A case report
Xiao-Rui Huang, Deng-Sheng Zhu, Ya-Hong Yu
Xiao-Rui Huang, Deng-Sheng Zhu, Ya-Hong Yu, Department of Biliopancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, Hubei Province, China
Author contributions: Huang XR performed the research and wrote the manuscript; Zhu DS followed up with the patient; Yu YH designed the research study and reviewed the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for the publication of any potentially identifiable images or data included in this article.
Conflict-of-interest statement: All authors declare that they have no relevant conflicts of interest to disclose regarding this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ya-Hong Yu, MD, Chief Physician, FRCS (Gen Surg), Professor, Department of Biliopancreatic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1095 Jie Fang Avenue, Wuhan 430000, Hubei Province, China. yuyahong615@sina.com
Received: April 28, 2025 Revised: June 4, 2025 Accepted: June 19, 2025 Published online: August 27, 2025 Processing time: 121 Days and 16.3 Hours
Abstract
BACKGROUND
Intraductal papillary mucinous neoplasm (IPMN) and intraductal papillary neoplasm of the bile duct (IPNB) are mucinous cystic tumors with intraductal papillary growth and malignant potential. Their concurrent occurrence is exceptionally rare.
CASE SUMMARY
A 58-year-old Chinese man presented with recurrent upper abdominal pain. Imaging and laboratory tests revealed lesions consistent with IPNB and IPMN. Postoperative pathological examination confirmed IPNB with high-grade dysplasia and main-duct type IPMN with low-grade dysplasia. The patient underwent extrahepatic bile duct resection with Roux-en-Y choledochoenterostomy and distal pancreatectomy. He had an excellent prognosis with no tumor recurrence during the 30-month follow-up.
CONCLUSION
This case emphasizes the importance of comprehensive preoperative assessment and individualized management for these complex tumors. Further research is needed to understand their pathogenesis and improve treatment strategies.
Core Tip: This case highlights the rare coexistence of intraductal papillary mucinous neoplasm (IPMN) and intraductal papillary neoplasm of the bile duct (IPNB) in a 58-year-old Chinese man presenting with abdominal pain. The patient underwent successful surgical resection and had an excellent prognosis with no recurrence during the 30-month follow-up. This case emphasizes the importance of comprehensive preoperative assessment using multiple imaging modalities and individualized management for complex tumors such as IPNB and IPMN.
