Li WB, Li J, Yu W, Gao JH. Short-term efficacy of laparoscopic radical resection for colorectal cancer and risk of unplanned reoperation after surgery. World J Gastrointest Surg 2025; 17(4): 102442 [DOI: 10.4240/wjgs.v17.i4.102442]
Corresponding Author of This Article
Jian-Hua Gao, Department of General Surgery, Yulin First Hospital, No. 93 Yuxi Avenue, High-tech Zone, Yulin 719000, Shaanxi Province, China. qtdypsy623@sina.com
Research Domain of This Article
Medicine, General & Internal
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Apr 27, 2025; 17(4): 102442 Published online Apr 27, 2025. doi: 10.4240/wjgs.v17.i4.102442
Short-term efficacy of laparoscopic radical resection for colorectal cancer and risk of unplanned reoperation after surgery
Wen-Bin Li, Jiang Li, Wei Yu, Jian-Hua Gao
Wen-Bin Li, Jiang Li, Wei Yu, Jian-Hua Gao, Department of General Surgery, Yulin First Hospital, Yulin 719000, Shaanxi Province, China
Author contributions: Li WB designed the research and wrote the first draft of the manuscript; Li WB and Gao JH contributed to conceiving the research and analyzing data, provided guidance for the research; Li WB, Li J, Yu W and Gao JH conducted the analysis; all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Ethic Committee of Yulin First Hospital.
Informed consent statement: Patients did not need to provide informed consent for the study, as anonymous clinical data were used for analysis.
Conflict-of-interest statement: There is no conflict of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jian-Hua Gao, Department of General Surgery, Yulin First Hospital, No. 93 Yuxi Avenue, High-tech Zone, Yulin 719000, Shaanxi Province, China. qtdypsy623@sina.com
Received: January 8, 2025 Revised: February 11, 2025 Accepted: March 7, 2025 Published online: April 27, 2025 Processing time: 79 Days and 23.5 Hours
Abstract
BACKGROUND
Surgery is the first choice of treatment for patients with colorectal cancer. Traditional open surgery imparts great damage to the body of the patient and can easily cause adverse stress reactions. With the continuous development of medical technology, laparoscopic minimally invasive surgery has shown great advantages for the treatment of patients with celiac disease.
AIM
To investigate the short-term efficacy of laparoscopic radical surgery and traditional laparotomy for the treatment of colorectal cancer, and the differences in the risk analysis of unplanned reoperation after operation.
METHODS
As the research subjects, this study selected 100 patients with colorectal cancer who received surgical treatment at the Yulin First Hospital from January 2018 to January 2022. Among them, 50 patients who underwent laparoscopic radical resection were selected as the research group and 50 patients who underwent traditional laparotomy were selected as the control group. Data pertaining to clinical indexes, gastrointestinal hormones, nutrition indexes, the levels of inflammatory factors, quality of life, Visual Analog Scale score, and the postoperative complications of the two groups of patients before and after treatment were collected, and the therapeutic effects in the two groups were analyzed and compared.
RESULTS
Compared with the control group, perioperative bleeding, peristalsis recovery time, and hospital stays were significantly shorter in the research group. After surgery, the levels of gastrin (GAS) and motilin (MTL) were decreased in both groups, and the fluctuation range of GAS and MTL observed in the research group was significantly lower than that recorded in the control group. The hemoglobin (Hb) levels increased after surgery, and the level of Hb in the research group was significantly higher compared with the control group. After the operation, the expression levels of tumor necrosis factor-α, interleukin-6, and C-reactive protein and the total incidence of complications were significantly lower in the research group compared with the control group. One year after the operation, the quality of life of the two groups was greatly improved, with the quality of life in the research group being significantly better.
CONCLUSION
Laparoscopy was effective for colorectal surgery by reducing the occurrence of complications and inflammatory stress reaction; moreover, the quality of life of patients was significantly improved, which warrants further promotion.
Core Tip: With the advancement of medical technology, laparoscopic colorectal cancer surgery began to be widely used in the clinic. A retrospective analysis of patients with colorectal cancer suggests that, compared with traditional open surgery, laparoscopic surgery has advantages, such as a smaller incision, lower intraoperative blood loss, shorter hospital stays, and faster recovery. Concomitantly, laparoscopic surgery is less stimulating to the digestive tract of patients, has a definite effect, can reduce the occurrence of complications, reduces the inflammatory stress response, and significantly improves the quality of life of patients, which is worthy of further promotion and application.
