Published online Mar 27, 2025. doi: 10.4240/wjgs.v17.i3.103431
Revised: January 11, 2025
Accepted: January 21, 2025
Published online: March 27, 2025
Processing time: 94 Days and 13.4 Hours
This letter responds to Wang et al's recent publication on endoscopic biliary stenting for malignant obstructive jaundice (MOJ) by offering constructive feedback and suggestions for future research. We commend the authors for their comprehensive study design and execution, which included a clear delineation of study groups and a robust set of outcome measures. We suggest that future studies incorporate additional biomarkers, such as serum levels of liver enzymes and bilirubin, to provide a more nuanced understanding of liver function changes post-intervention. The study's focus on short-term survival rates is appreciated, but we recommend exploring longer-term follow-up periods to capture the full spectrum of survival outcomes. Additionally, the inclusion of quality of life assessments using validated instruments could offer a more holistic view of patient outcomes. From a critical care perspective, we advocate for the integration of advanced imaging techniques to better characterize biliary anatomy and potentially predict treatment response or complications. We believe that incor
Core Tip: The core tip of the manuscript is to evaluate the efficacy of endoscopic biliary stenting for malignant obstructive jaundice and compare it with the standard palliative approach, percutaneous transhepatic biliary drainage. The study suggests incorporating additional biomarkers for a nuanced understanding of liver function changes and emphasizes the importance of long-term follow-up to assess survival outcomes and the durability of palliative effects. It also highlights the need for quality of life assessments and advanced imaging techniques to predict treatment response and complications, contributing to a more holistic view of patient outcomes.