Zhi L, Chen ZH, Deng J. Parameter changes and influencing factors in sixty patients with interventional surgery for liver cancer diagnoses. World J Gastrointest Surg 2025; 17(2): 99581 [DOI: 10.4240/wjgs.v17.i2.99581]
Corresponding Author of This Article
Jun Deng, Chief Physician, Department of Interventional, Affiliated Wuxi Fifth Hospital of Jiangnan University (The Fifth People’s Hospital of Wuxi), No. 1215 Guangrui Road, Liangxi District, Wuxi 214000, Jiangsu Province, China. dengjun770626@sohu.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2025; 17(2): 99581 Published online Feb 27, 2025. doi: 10.4240/wjgs.v17.i2.99581
Parameter changes and influencing factors in sixty patients with interventional surgery for liver cancer diagnoses
Lin Zhi, Zhi-Hai Chen, Jun Deng
Lin Zhi, Electrocardiographic Room, Affiliated Wuxi Fifth Hospital of Jiangnan University (The Fifth People’s Hospital of Wuxi), Wuxi 214000, Jiangsu Province, China
Zhi-Hai Chen, Department of Pulmonary and Critical Care Medicine, Wuxi 9th Affiliated Hospital of Soochow University, Wuxi 214000, Jiangsu Province, China
Jun Deng, Department of Interventional, Affiliated Wuxi Fifth Hospital of Jiangnan University (The Fifth People’s Hospital of Wuxi), Wuxi 214000, Jiangsu Province, China
Author contributions: Zhi L designed the study and performed the research; Zhi L and Deng J analyzed the data and wrote the manuscript; Zhi L, Chen ZH, and Deng J read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Committee of Affiliated Wuxi Fifth Hospital of Jiangnan University (The Fifth People’s Hospital of Wuxi) (No. Wuxi Fifth Academy Thesis Lunzi 2024-022-1).
Informed consent statement: All study participants or their legal guardians provided written informed consent for personal and medical data collection before enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: No other data is available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Deng, Chief Physician, Department of Interventional, Affiliated Wuxi Fifth Hospital of Jiangnan University (The Fifth People’s Hospital of Wuxi), No. 1215 Guangrui Road, Liangxi District, Wuxi 214000, Jiangsu Province, China. dengjun770626@sohu.com
Received: November 7, 2024 Revised: December 11, 2024 Accepted: December 25, 2024 Published online: February 27, 2025 Processing time: 76 Days and 2.4 Hours
Abstract
BACKGROUND
The development of hepatocellular carcinoma (HCC) is influenced by multiple factors. Interventional therapy offers an effective treatment option for patients with unresectable intermediate-to-advanced HCC. Interventional therapy can induce electrocardiographic (ECG) abnormalities that may be associated with liver dysfunction, electrolyte disorders, and cardiac injury.
AIM
To explore the ECG alterations and determinants following interventional therapy in patients with HCC.
METHODS
Sixty patients undergoing interventional treatment for liver cancer were selected as study participants. According to the results of the dynamic ECG examination 1 day after surgery, the patients were divided into an abnormal group (n = 21) and a nonabnormal group (n = 39). With the help of dynamic ECG examination, the ECG parameters were compared and the baseline data of patients was recorded in the two groups.
RESULTS
The 24 hours QT interval variability, 24 hours normal atrial polarization to ventricular polarization (R-R) interval (standard deviation), 24 hours consecutive 5 minutes normal R-R interval, and 24 hours continuous 5 minutes normal R-R interval (standard deviation mean) were lower than patients in the nonabnormal group (P < 0.05). The logistic analysis showed that age > 60 years, liver function grade B, and postoperative body temperature 38 °C were risk factors for abnormal dynamic electrocardiogram in patients with liver cancer intervention (P < 0.05).
CONCLUSION
Interventional therapy for HCC can lead to ECG abnormalities, underscoring the clinical need for enhanced cardiac monitoring to mitigate myocardial complications.
Core Tip: The Electrocardiographic abnormalities of liver cancer patients should be clarified as soon as possible, and targeted intervention measures are needed for the risk factors affecting their electrocardiographic abnormalities, especially for those undergoing interventional therapy.
