Fei S, Wu WD, Zhang HS, Liu SJ, Li D, Jin B. Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature. World J Gastrointest Surg 2024; 16(8): 2724-2734 [PMID: 39220064 DOI: 10.4240/wjgs.v16.i8.2724]
Corresponding Author of This Article
Wei-Dong Wu, PhD, Doctor, Department of Thoracic and Cardiovascular Surgery, Guangzhou Red Cross Hospital of Jinan University, No. 396 Tongfu Zhong Lu, Haizhu District, Guangzhou 510000, Guangdong Province, China. feisong2022@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2724-2734 Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2724
Primary coexisting adenocarcinoma of the colon and neuroendocrine tumor of the duodenum: A case report and review of the literature
Song Fei, Wei-Dong Wu, Han-Shuo Zhang, Shao-Jie Liu, Dan Li, Bo Jin
Song Fei, Wei-Dong Wu, Dan Li, Bo Jin, Department of Thoracic and Cardiovascular Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China
Han-Shuo Zhang, Shao-Jie Liu, Department of Gastrointestinal Surgery, Guangzhou Red Cross Hospital of Jinan University, Guangzhou 510000, Guangdong Province, China
Author contributions: Fei S and Zhang HS participated in the diagnosis and drafted the manuscript; Liu SJ, Fei S, and Zhang HS decided and performed the surgical protocol of this patient; Li D and Jin B reviewed the manuscript; Wu WD revised and approved the manuscript; All authors have read and approved the final manuscript.
Supported bythe Guangzhou Science and Technology Program Project, No. 201902010003.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Dong Wu, PhD, Doctor, Department of Thoracic and Cardiovascular Surgery, Guangzhou Red Cross Hospital of Jinan University, No. 396 Tongfu Zhong Lu, Haizhu District, Guangzhou 510000, Guangdong Province, China. feisong2022@163.com
Received: April 5, 2024 Revised: May 13, 2024 Accepted: June 7, 2024 Published online: August 27, 2024 Processing time: 133 Days and 5.6 Hours
Abstract
BACKGROUND
Neuroendocrine tumors (NETs) arise from the body’s diffuse endocrine system. Coexisting primary adenocarcinoma of the colon and NETs of the duodenum (D-NETs) is a rare occurrence in clinical practice. The classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been determined.
CASE SUMMARY
We report the details of a case involving female patient with coexisting primary adenocarcinoma of the colon and a D-NET diagnosed by imaging and surgical specimens. The tumors were treated by surgery and four courses of chemotherapy. The patient achieved a favorable clinical prognosis.
CONCLUSION
Coexisting primary adenocarcinoma of the colon and D-NET were diagnosed by imaging, laboratory indicators, and surgical specimens. Surgical resection combined with chemotherapy was a safe, clinically effective, and cost-effective treatment.
Core Tip: Coexisting primary adenocarcinoma of the colon and neuroendocrine tumor of the duodenum (D-NET) is a rare occurrence in clinical practice. We report the details of a case involving a female patient with coexisting primary adenocarcinoma of the colon and D-NET diagnosed by imaging and surgical specimens. The tumors were treated by surgery and four courses of chemotherapy. The patient achieved a favorable clinical prognosis. The classification and treatment criteria for D-NETs combined with a second primary cancer have not yet been determined. Our experience may help others to diagnose and manage similar patients.
