Scientometrics
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2702-2718
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2702
Global research landscape of Peutz-Jeghers syndrome and successful endoscopic management of intestinal intussusception in patients with recurrent laparotomies
Qi Sun, Xiao-Ying Wang, Guang-Jin Guo, Lei Wang, Li-Min Meng, Yun-Fei Guo, Tao Sun, Shou-Bin Ning
Qi Sun, Xiao-Ying Wang, Lei Wang, Tao Sun, Shou-Bin Ning, Department of Gastroenterology, Air Force Medical Center, Beijing 100142, China
Xiao-Ying Wang, College of Life Science, Northwest University, Xi'an 710069, Shaanxi Province, China
Guang-Jin Guo, Clinical Medical Laboratory, Air Force Medical Center, Beijing 100142, China
Li-Min Meng, Department of Medical Imaging, Air Force Medical Center, Beijing 100142, China
Yun-Fei Guo, Department of Pathology, Air Force Medical Center, Beijing 100142, China
Co-first authors: Qi Sun and Xiao-Ying Wang.
Co-corresponding authors: Tao Sun and Shou-Bin Ning.
Author contributions: Sun Q and Wang XY designed the study, acquired and analyzed data and wrote the manuscript; Guo GJ and Wang L collected the data; Meng LM and Guo YF contributed analytic tools; Sun T and Ning SB provided supervision and guidance, reviewed and edited the manuscript and handled submission and communication. All authors have read and approved the final manuscript. Sun Q and Wang XY have both made significant and equal intellectual contributions to this study, as highlighted below. Study design: Both Sun Q and Wang XY actively participated in designing the study and formulating the experimental protocols. Data acquisition and analysis: Sun Q was responsible for acquiring experimental data and conducting initial analyses to ensure accuracy and reliability. Wang XY further analyzed the data, performed statistical processing and interpreted the results. Manuscript writing: Both Sun Q and Wang XY collaboratively wrote the initial draft of the manuscript, with each author responsible for different sections. They worked together through multiple revisions and discussions to finalize the manuscript. As co-corresponding authors, Sun T and Ning SB made significant contributions in the following areas: Supervision and guidance: Sun T provided overall guidance for the study, including topic selection and suggestions on experimental methods. Ning SB supervised the progression of the experiments and resolved technical issues encountered during the research. Manuscript revisions: Both Sun T and Ning SB reviewed and extensively revised the manuscript to ensure the clarity of results and maintain academic rigor. Submission and communication: Ning SB handled the communication with the journal editorial office and dealt with initial feedback and revision requests. Sun T assisted with submission and ensured the completeness and timely submission of all necessary documents. We believe that this detailed contributions statement supports our designation of co-first authors and co-corresponding authors, accurately reflecting the contributions of each author to the study.
Supported by Capital Health Development Research Special Project, No. 2020-4-5123.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shou-Bin Ning, PhD, Chief Doctor, Department of Gastroenterology, Air Force Medical Center, No. 30 Fucheng Road, Haidian District, Beijing 100142, China. shoubinning@126.com
Received: March 13, 2024
Revised: June 7, 2024
Accepted: June 25, 2024
Published online: August 27, 2024
Processing time: 156 Days and 12.7 Hours
Abstract
BACKGROUND

Peutz-Jeghers syndrome (PJS) has brought significant physical, psychological and economic burdens on the patients and their families due to its early onset, diagnostic and therapeutic challenges and increased recurrence risk.

AIM

To explore the current research status and emerging hotspots of PJS.

METHODS

Studies on PJS published during 1994-2023 were gathered based on Web of Science Core Collection. Additionally, a case of PJS-induced intestinal intussusception, successfully treated with endoscopic methods despite three laparotomies, was highlighted. Comprehensive bibliometric and visual analysis were conducted with VOSviewer, R and CiteSpace.

RESULTS

Altogether 1760 studies were identified, indicating a steady increase in the publication number. The United States had the highest influence, whereas the University of Helsinki emerged as the leading institution, and Aaltonen LA from the University of Helsinki was the most prolific author. Cancer Research, Oncogene and Endoscopy were the top three journals based on H-index. Keyword burst direction analysis revealed that "cancer risk", "management", "surveillance" and "familial pancreatic cancer" were the potential hotspots for investigation. Additionally, "early detection", "capsule endoscopy", "clinical management", "double-balloon endoscopy", "familial pancreatic cancer" and "molecular genetic basis" were identified as the key clusters of co-cited references. Endoscopic polypectomy remained effective on resolving intestinal intussusception in patients who underwent three previous laparotomies.

CONCLUSION

In the last three decades, global publications related to PJS show a steadily increasing trend in number. Endoscopic management is currently a research hotspot.

Keywords: Peutz-Jeghers syndrome; Endoscopy; Management; Cancer; Microbiota; Bibliometric

Core Tip: This study investigated the current situation of Peutz-Jeghers syndrome and identified "cancer risk" and "treatment management" as the research focuses. In addition, it also emphasized the significant therapeutic effect of endoscopic polypectomy, even in cases with intussusception after the first three abdominal surgeries. These findings provide valuable insights for diagnosing and treating such patients by clinical doctors, thereby improving patient life quality and prognosis.