Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Aug 27, 2024; 16(8): 2640-2648
Published online Aug 27, 2024. doi: 10.4240/wjgs.v16.i8.2640
Relationship between postoperative rehabilitation style, gastrointestinal function, and inflammatory factor levels in children with intussusception
Xue-Yan Wei, Hong-Chang Huo, Xin Li, Su-Li Sun, Jun Zhang
Xue-Yan Wei, Su-Li Sun, Department of Outpatient, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050090, Hebei Province, China
Hong-Chang Huo, Jun Zhang, Department of Pediatric Surgery, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050090, Hebei Province, China
Xin Li, Department of Nursing, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050090, Hebei Province, China
Author contributions: Zhang J designed research; Wei XY performed research; Huo HC and Li X contributed new reagents or analytic tools; Sun SL analyzed data; Wei XY wrote the paper.
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Shijiazhuang City Maternal and Child Health Care Hospital.
Informed consent statement: All subjects understood and agreed to the study protocol and voluntarily signed the informed consent form.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: We do not have additional data.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house Author and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Zhang, BSc, Chief Doctor, Department of Pediatric Surgery, Shijiazhuang Maternal and Child Health Hospital, No. 358 Xinhua Road, Xinhua District, Shijiazhuang 050090, Hebei Province, China. wxy18731160957@126.com
Received: June 17, 2024
Revised: July 10, 2024
Accepted: July 22, 2024
Published online: August 27, 2024
Processing time: 60 Days and 3.1 Hours
Abstract
BACKGROUND

Intussusception occurs in children and progresses rapidly. If not treated in time, it may lead to secondary complications such as intestinal perforation, which affect the quality of life and health of children. Surgery is the most common clinical treatment and has a good effect. However, the postoperative prognosis of children with intussusception has a correlation with the postoperative rehabilitation method. Therefore, in this study, we explored the relationship between postoperative rehabilitation, gastrointestinal function, and the expression of inflammatory factors in children with intussusception.

AIM

To explore the relationship between postoperative rehabilitation, gastrointestinal function, and inflammatory factor levels in children with intussusception.

METHODS

The medical records of 18 children who were admitted to our hospital for intussusception surgery between October 2022 and May 2024 were retrospectively reviewed. The patients were divided into the routine nursing group (n = 6) and rehabilitation training group (n = 12) according to the postoperative rehabilitation method. The general data, gastrointestinal function, and inflammatory factor levels of the two groups were statistically analyzed. Pearson correlation analysis of gastrointestinal function, inflammatory factors, and postoperative rehabilitation was performed.

RESULTS

We found no significant intergroup differences in sex, age, or disease course (P > 0.05). The times to first defecation, bowel sound recovery, and anal exhaust were shorter and inflammatory factor levels were lower in the rehabilitation training group than in the routine nursing group (P < 0.05). Pearson correlation analysis showed that gastrin and motilin levels were positively correlated with postoperative rehabilitation (P < 0.05). Interleukin (IL)-2, IL-4, IL-6, IL-10, high-sensitivity C-reactive protein, and tumor necrosis factor-α levels were negatively correlated with postoperative rehabilitation (P < 0.05). Gastrointestinal function was positively correlated (P < 0.05), and levels of inflammatory factors were negatively correlated with postoperative recovery time (P < 0.05).

CONCLUSION

We found a positive correlation between gastrointestinal function and postoperative rehabilitation training, and a negative correlation between inflammatory factor levels and rehabilitation training in children with intussusception.

Keywords: Children with intussusception; Postoperative rehabilitation mode; Gastrointestinal function; Inflammatory factors

Core Tip: In this study, we found that postoperative rehabilitation training in children with intussusception could accelerate the recovery of gastrointestinal function, elevate the levels of gastrin and migratory complex wave, and at the same time, significantly reduce the inflammatory factors, such as interleukin (IL)-2, IL-4, IL-6, IL-10, high-sensitivity C-reactive protein, and tumor necrosis factor-α. This study confirms that the rehabilitation training has a significant effect on the improvement of gastrointestinal function and the alleviation of inflammation, which is an important revelation in the clinical treatment.