Copyright
©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Advancements in nutritional diagnosis and support strategies during the perioperative period for patients with liver cancer
Xiao-Qin Li, Yun Liang, Chen-Feng Huang, Sui-Ning Li, Lei Cheng, Chuan You, Yao-Xia Liu, Tao Wang
Xiao-Qin Li, Lei Cheng, Chuan You, Department of Hepatobiliary Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Yun Liang, Department of Paediatric Surgery, The Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, Sichuan Province, China
Chen-Feng Huang, Sui-Ning Li, Department of Cardiovascular Surgery, The First Affiliated Hospital, Jinan University, Guangzhou 510632, Guangdong Province, China
Yao-Xia Liu, Department of Geriatric Endocrinology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu 610072, Sichuan Province, China
Tao Wang, Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Tao Wang, Department of Pediatrics, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Chengdu 610041, Sichuan Province, China
Co-corresponding authors: Yao-Xia Liu and Tao Wang.
Author contributions: Li XQ was responsible for the study concept and manuscript preparation; Liang Y and Huang CF was responsible for the intellectual content and manuscript review; Li SN, Cheng L, and You C were involved in the literature search and manuscript editing; Liu YX and Wang T performed the role of guarantor for the integrity and study design of the study; All authors have read and approved this article. Wang T and Liu YX, as co-corresponding authors, played an indispensable role in the conception, design, and writing of the manuscript, and provided financial support for it. Liu YX assisted and was responsible for re-analyzing and re-interpreting the data, creating figures, and conducting comprehensive literature searches. Wang T supervised the entire process of the project, as well as the preparation and submission of the current version of the manuscript. The collaboration between Wang T and Liu YX is crucial for the publication of this manuscript.
Supported by National Natural Science Foundation of China, No 81701888; Science and Technology Program of Sichuan Province, No. 2023YFS0206; and Scientific Research Project of Sichuan Cadre Health Committee, No. 2022-211.
Conflict-of-interest statement: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See:
https://creativecommons.org/Licenses/by-nc/4.0/ Corresponding author: Tao Wang, MD, Chief Physician, Department of Pediatric Cardiology, West China Second University Hospital, Sichuan University, No. 20 The 3
rd Section, South Renmin Road, Chengdu 610041, Sichuan Province, China.
44871875@qq.com
Received: March 8, 2024
Revised: May 27, 2024
Accepted: June 24, 2024
Published online: August 27, 2024
Processing time: 161 Days and 6.3 Hours
Liver cancer represents a grave hepatic condition and constitutes a significant global health concern. Surgical resection remains the principal therapeutic modality for liver cancer. Nevertheless, perioperative malnutrition exerts a notable impact on patients with liver cancer, emerging as an independent risk factor for disease mortality and adverse outcomes. Hence, precise nutritional diagnosis and timely nutritional support hold the potential to enhance therapeutic efficacy and quality of life for liver cancer patients. This study represents a meticulous foray into the literature, extracting data from PubMed, Web of Science, and EMBASE databases, with a focus on the past 5 years. It scrutinizes the impact of malnutrition on patients undergoing liver cancer surgery, the etiological underpinnings of malnutrition within this patient cohort, the critical assessment of perioperative nutritional status, and the strategic approaches to nutritional support. Utilizing rigorous inclusion and exclusion criteria, the amassed scholarly works are meticulously synthesized, methodically organized, and categorically elaborated upon. Ultimately, the authors propose the incorporation of a multidisciplinary nutrition management team during the perioperative period, comprising nutritionists, pharmacists, physicians, nurses, psychologists, and rehabilitation therapists, among other specialized professionals. Together, they collaborate to devise and implement personalized nutritional support plans, monitor patients’ nutritional status, and make necessary adjustments as required. Through comprehensive management and intervention, improvements in the nutritional status of liver cancer patients can be achieved, thereby enhancing surgical success rates and facilitating postoperative recovery. It is believed that this manuscript will offer valuable insights to advance the nutritional management during the perioperative phase of liver cancer, aiding in ameliorating patients' nutritional status and treatment outcomes.
Core Tip: Liver cancer is a severe hepatic ailment, constituting a paramount global health concern. Nonetheless, the impact of perioperative malnutrition on patients with liver cancer is notably profound, emerging as an independent risk factor for disease mortality and adverse outcomes. This manuscript provides a comprehensive review focusing on the influence of malnutrition on liver cancer surgical patients, the etiology of malnutrition in liver cancer patients, perioperative nutritional status assessment, and nutritional support strategies. It is believed that this paper will offer reference opinions and theoretical groundwork to aid in the formulation of standardized perioperative nutritional support protocols.
