Case Report
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2024; 16(6): 1918-1925
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1918
Malignant myopericytoma originating from the colon: A case report
Heng-Li Zhang, Min Zhang, Jing-Qiang Guo, Fang-Nan Wu, Jin-De Zhu, Chao-Yong Tu, Xin-Liang Lv, Kun Zhang
Heng-Li Zhang, Jing-Qiang Guo, Fang-Nan Wu, Jin-De Zhu, Chao-Yong Tu, Xin-Liang Lv, Kun Zhang, Department of General Surgery, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, Zhejiang Province, China
Min Zhang, Department of Pathology, The Fifth Affiliated Hospital of Wenzhou Medical University, Lishui 323000, Zhejiang Province, China
Author contributions: Zhang HL participated in the formulation of clinical diagnosis and treatment plan, collected the clinical data, and wrote the manuscript; Zhang M performed the histopathological diagnosis and contributed to the manuscript drafting; Guo JQ collected the clinical data and performed the follow-up; Wu FN contributed to the manuscript drafting; Zhu JD, Tu CY, and Lv XL supervised the diagnosis and treatment of this patient; Zhang K edited and critically revised the manuscript.
Informed consent statement: Informed written consent was obtained from the patients for the publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest to disclose.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Kun Zhang, MM, Chief Physician, Department of General Surgery, The Fifth Affiliated Hospital of Wenzhou Medical University, No. 289 Kuocang Road, Lishui 323000, Zhejiang Province, China. zhangkun836@163.com
Received: January 29, 2024
Revised: March 20, 2024
Accepted: April 17, 2024
Published online: June 27, 2024
Processing time: 153 Days and 0.1 Hours
Abstract
BACKGROUND

Myopericytoma is a benign tumor that typically occurs within subcutaneous tissue and most often involves the distal extremities, followed by the proximal extremities, neck, thoracic vertebrae and oral cavity. Complete resection is often curative. Malignant myopericytoma is extremely rare and has a poor prognosis. Here, we report for the first time a case of malignant myopericytoma originating from the colon.

CASE SUMMARY

A 69-year-old male was admitted to our hospital with right upper quadrant pain for five days. Imaging suggested a liver mass with hemorrhage. A malignant hepatic tumor was the initial diagnosis. Surgical resection was performed after a complete preoperative work up. Initial postoperative pathology suggested that the mass was a malignant myoblastoma unrelated to the liver. Four months after the first surgery, an enhanced computed tomography (CT) scan revealed a recurrence of the tumor. The diagnosis of malignant myopericytoma derived from the colon was confirmed on histopathological examination of the specimen from the second surgery. The patient did not return to the hospital regularly for surveillance. The first postoperative abdominal CT examination six months after the second surgery demonstrated multiple liver metastases. Survival time between the diagnosis of the tumor to death was approximately one year.

CONCLUSION

Malignant myopericytoma is a rare cancer. Preoperative diagnosis may be difficult. Due to a lack of treatment options, prognosis is poor.

Keywords: Malignant myopericytoma; Liver tumor; Colonic neoplasms; Abdominal pain; Case report

Core Tip: The incidence of malignant myopericytoma is very low and prognosis is poor. Presently, there is no ideal intervention. In this case, the patient was initially admitted to hospital with pain secondary to a hemorrhage into a liver tumor. After two surgeries, the patient was definitively diagnosed with a malignant myopericytoma originating in the colon. Due to the lack of comprehensive antitumor therapy and poor patient compliance, the tumor progressed rapidly. The patient’s survival was only one year. In view of the lack of diagnostic and treatment guidelines, future clinical and basic science research on myopericytomas is warranted and can hopefully improve prognosis.