Editorial
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Jun 27, 2024; 16(6): 1493-1500
Published online Jun 27, 2024. doi: 10.4240/wjgs.v16.i6.1493
Intestinal Behçet's disease: A review of clinical diagnosis and treatment
Ying Liu, Feng Gao, Ding-Quan Yang, Yan Jiao
Ying Liu, Feng Gao, Department of General Surgery, The Affiliated Hospital to Changchun University of Chinese Medicine, Changchun 130021, Jilin Province, China
Ding-Quan Yang, Department of Gastrointestinal and Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130033, Jilin Province, China
Yan Jiao, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Liu Y contributed to the writing, editing of the manuscript and table, and literature search; Gao F and Yang DQ contributed to the discussion, design of the manuscript and literature search; Jiao Y designed the overall concept and outline of the manuscript. All authors have read and approve the final manuscript.
Conflict-of-interest statement: The authors have claimed no conflict of interests.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Jiao, MD, PhD, Surgeon, Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, No. 1 Xinmin Street, Changchun 130021, Jilin Province, China. lagelangri1@126.com
Received: February 15, 2024
Revised: April 13, 2024
Accepted: April 26, 2024
Published online: June 27, 2024
Processing time: 135 Days and 12.1 Hours
Abstract

Behçet's disease (BD) is a chronic inflammatory disorder prone to frequent recurrences, with a high predilection for intestinal involvement. However, the efficacy and long-term effects of surgical treatment for intestinal BD are unknown. In the current issue of World J Gastrointest Surg, Park et al conducted a retrospective analysis of 31 patients with intestinal BD who received surgical treatment. They found that elevated C-reactive protein levels and emergency surgery were poor prognostic factors for postoperative recurrence, emphasizing the adverse impact of severe inflammation on the prognosis of patients with intestinal BD. This work has clinical significance for evaluating the postoperative condition of intestinal BD. The editorial attempts to summarize the clinical diagnosis and treatment of intestinal BD, focusing on the impact of adverse factors on surgical outcomes. We hope this review will facilitate more precise postoperative management of patients with intestinal BD by clinicians.

Keywords: Intestinal Behçet's disease, Diagnosis, Treatment, Surgery, Recurrence

Core Tip: Intestinal Behçet's disease (BD) is the gastrointestinal manifestation of BD, characterized primarily by intestinal ulcerations. The differential diagnosis of intestinal BD is challenging, the disease course is prolonged, and surgical intervention is often necessary to achieve cure or remission. Despite surgical treatment, postoperative recurrence and reoperation rates remain high. Understanding the timing of surgery and factors associated with postoperative recurrence is critical for standardized surgical and follow-up management of patients with intestinal BD.