Letter to the Editor
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2024; 16(5): 1482-1484
Published online May 27, 2024. doi: 10.4240/wjgs.v16.i5.1482
Exploring predictive markers for liver failure post-hepatectomy in hepatocellular carcinoma patients
Shi-Yan Zhang, Xiong-Jian Ma, Xue-Xia Zhu, Na Cai
Shi-Yan Zhang, Xiong-Jian Ma, Xue-Xia Zhu, Na Cai, Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, Fuding 355200, Fujian Province, China
Author contributions: Zhang SY and Ma XJ designed and performed research; Zhu XX wrote the comment; and Cai N revised the comment. All the authors listed have read and approved the final manuscript.
Conflict-of-interest statement: The authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Shi-Yan Zhang, MD, Director, Doctor, Department of Clinical Laboratory, Fuding Hospital, Fujian University of Traditional Chinese Medicine, No. 120 South Road of Old City, Fuding 355200, Fujian Province, China. myebox@139.com
Received: February 1, 2024
Revised: April 9, 2024
Accepted: April 17, 2024
Published online: May 27, 2024
Abstract

This letter to the editor addresses the study titled “Predictive value of NLR, Fib4, and APRI in the occurrence of liver failure after hepatectomy in patients with hepatocellular carcinoma” by Kuang et al in the World Journal of Gastrointestinal Surgery. The study acknowledges the comprehensive patient data analysis while suggesting that there is a need for further discussion on the clinical applicability of these markers across diverse patient populations. This letter recommends prospective studies for validation and considers the influence of confounding factors. This finding underscores the significance of this study in improving hepatocellular carcinoma management.

Keywords: Neutrophil-to-lymphocyte ratio, Hepatocellular carcinoma, Liver failure, Hepatectomy, Letter to the Editor, Commentary

Core Tip: Acknowledges the study's comprehensive analysis and its contribution to hepatocellular carcinoma management. These findings suggest further exploration of the clinical applicability of the neutrophil-lymphocyte ratio, fibrosis index based on four factors, and aspartate aminotransferase-to-platelet ratio index in diverse patient groups. Prospective studies for the validation of these findings are recommended. This highlights the importance of considering the confounding factors in future research.