Published online Feb 27, 2024. doi: 10.4240/wjgs.v16.i2.503
Peer-review started: November 27, 2023
First decision: December 29, 2023
Revised: January 6, 2024
Accepted: February 5, 2024
Article in press: February 5, 2024
Published online: February 27, 2024
Although en bloc dissection of hepatic hilum lymph nodes has many advantages in radical tumor treatment, the feasibility and safety of this approach for laparoscopic pancreaticoduodenectomy (LPD) require further clinical evaluation and investigation.
To explore the application value of the "five steps four quadrants" modularized en bloc dissection technique for accessing hepatic hilum lymph nodes in LPD patients.
A total of 52 patients who underwent LPD via the "five steps four quadrants" modularized en bloc dissection technique for hepatic hilum lymph nodes from April 2021 to July 2023 in our department were analyzed retrospectively. The patients' body mass index (BMI), preoperative laboratory indices, intraoperative variables and postoperative complications were recorded. The relationships between preoperative data and intraoperative lymph node dissection time and blood loss were also analyzed.
Among the 52 patients, 36 were males and 16 were females, and the average age was 62.2 ± 11.0 years. There were 26 patients with pancreatic head cancer, 16 patients with periampullary cancer, and 10 patients with distal bile duct cancer. The BMI was 22.3 ± 3.3 kg/m², and the median total bilirubin (TBIL) concentration was 57.7 (16.0-155.7) µmol/L. All patients successfully underwent the "five steps four quadrants" modularized en bloc dissection technique without lymph node clearance-related complications such as postoperative bleeding or lymphatic leakage. Correlation analysis revealed significant associations between preoperative BMI (r = 0.3581, P = 0.0091), TBIL level (r = 0.2988, P = 0.0341), prothrombin time (r = 0.3018, P = 0.0297) and lymph node dissection time. Moreover, dissection time was significantly correlated with intraoperative blood loss (r = 0.7744, P < 0.0001). Further stratified analysis demonstrated that patients with a preoperative BMI ≥ 21.9 kg/m² and a TIBL concentration ≥ 57.7 μmol/L had significantly longer lymph node dissection times (both P < 0.05).
The "five steps four quadrants" modularized en bloc dissection technique for accessing the hepatic hilum lymph node is safe and feasible for LPD. This technique is expected to improve the efficiency of hepatic hilum lymph node dissection and shorten the learning curve; thus, it is worthy of further clinical promotion and application.
Core Tip: Although en bloc dissection of hepatic hilum lymph nodes has many advantages, the feasibility and safety of this approach for laparoscopic pancreaticoduodenectomy (LPD) requires further clinical investigation. We showed that the emerging technique of "five steps four quadrants" modularized en bloc dissection of hepatic hilum lymph nodes is safe and feasible for LPD. In this technique, a preoperative elevated body mass index, total bilirubin concentration, and prothrombin time increase the difficulty of lymph node dissection. This approach is expected to improve the efficiency of hepatic hilum lymph node dissection and shorten the learning curve; thus, this technique is worthy of further clinical promotion and application.