Bae SU. Prognostic impact of preoperative nutritional and immune inflammatory parameters on liver cancer. World J Gastrointest Surg 2024; 16(2): 266-269 [PMID: 38463370 DOI: 10.4240/wjgs.v16.i2.266]
Corresponding Author of This Article
Sung Uk Bae, Doctor, MD, PhD, Associate Professor, Doctor, Department of Surgery, School of Medicine, Dongsan Medical Center, Keimyung University, 1035, Dalgubeol-daero, Dalseo-gu, Daegu KS002, South Korea. sabiston0000@hanmail.net
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Editorial
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Feb 27, 2024; 16(2): 266-269 Published online Feb 27, 2024. doi: 10.4240/wjgs.v16.i2.266
Prognostic impact of preoperative nutritional and immune inflammatory parameters on liver cancer
Sung Uk Bae
Sung Uk Bae, Department of Surgery, School of Medicine, Dongsan Medical Center, Keimyung University, Daegu KS002, South Korea
Author contributions: Bae SU designed research; Bae SU performed research; Bae SU analyzed data; Bae SU wrote the letter; and Bae SU revised the letter.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sung Uk Bae, Doctor, MD, PhD, Associate Professor, Doctor, Department of Surgery, School of Medicine, Dongsan Medical Center, Keimyung University, 1035, Dalgubeol-daero, Dalseo-gu, Daegu KS002, South Korea. sabiston0000@hanmail.net
Received: November 21, 2023 Peer-review started: November 21, 2023 First decision: December 17, 2023 Revised: January 2, 2024 Accepted: January 29, 2024 Article in press: January 29, 2024 Published online: February 27, 2024
Abstract
The immune response to tissue damage or infection involves inflammation, a multifaceted biological process distinguished by immune cell activation, mediator secretion, and immune cell recruitment to the site of injury. Several blood-based immune-inflammatory biomarkers with prognostic significance in malignancies have been identified. In this issue of the World Journal of Gastrointestinal Surgery, they examined the prognosis of liver cancer radical resection in relation to preoperative systemic immune-inflammation and nutritional risk indices. Comparing older and younger individuals often reveals compromised nutritional and immunological statuses in the former. Therefore, performing preoperative evaluations of the nutritional status and immunity in geriatric patients is critical. In addition to being a primary treatment modality, radical resection is associated with a significant mortality rate following surgery. Insufficient dietary consumption and an elevated metabolic rate within tumor cells contribute to the increased probability of malnutrition associated with the ailment, consequently leading to a substantial deterioration in prognosis. Recent studies, reinforce the importance of nutritional and immune-inflammatory biomarkers. Prior to surgical intervention, geriatric nutritional risk and systemic immune-inflammatory indices should be prioritized, particularly in older patients with malignant diseases.
Core Tip: In this issue of the World Journal of Gastrointestinal Surgery, they examined the prognosis of liver cancer radical resection in relation to the preoperative systemic immune-inflammation and geriatric nutritional risk indices. They provided further evidence for the significance of nutritional and immune-inflammatory biomarkers in patients undergoing hepatocellular carcinoma treatment.
