Yang LC, Wu GT, Wu Q, Peng LX, Zhang YW, Yao BJ, Liu GL, Yuan LW. Surgical management of duodenal Crohn's disease. World J Gastrointest Surg 2023; 15(6): 1159-1168 [PMID: 37405094 DOI: 10.4240/wjgs.v15.i6.1159]
Corresponding Author of This Article
Lian-Wen Yuan, PhD, Additional Professor, Chief Physician, Department of Geriatric Surgery, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. yuanlianwen@csu.edu.cn
Research Domain of This Article
Surgery
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Li-Chao Yang, Qiang Wu, Liang-Xin Peng, Ya-Wei Zhang, Bao-Jia Yao, Gang-Lei Liu, Lian-Wen Yuan, Department of Geriatric Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Li-Chao Yang, Qiang Wu, Liang-Xin Peng, Ya-Wei Zhang, Bao-Jia Yao, Gang-Lei Liu, Lian-Wen Yuan, Department of General Surgery, The Second Xiangya Hospital of Central South University, Changsha 410011, Hunan Province, China
Guo-Tao Wu, Department of General Surgery, The Seventh Affiliated Hospital, University of South China, Changsha 410119, Hunan Province, China
Author contributions: Yang LC analyzed the data, prepared the figures and wrote the manuscript; Wu GT, Wu Q, Peng LX, Zhang YW and Yao BJ collected some data and contributed to manuscript preparation; Liu GL and Yuan LW contributed to the revision of the article; all authors have read the paper and approved the final submission.
Supported bythe National Natural Science Foundation of China, No. 81970493 and No. 82270590; and the National Natural Science Foundation of Hunan Province, No. 2021JJ30973 and No. 2021JJ40844.
Institutional review board statement: The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Ethics Committee of the Second Xiangya Hospital of Central South University (Approval No. 2022-155).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Data sharing statement: The data available from the corresponding author at yuanlianwen@csu.edu.cn or liuganglei@csu.edu.cn. Participants gave informed consent for data sharing.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Lian-Wen Yuan, PhD, Additional Professor, Chief Physician, Department of Geriatric Surgery, The Second Xiangya Hospital of Central South University, No. 139 Renmin Middle Road, Changsha 410011, Hunan Province, China. yuanlianwen@csu.edu.cn
Received: February 21, 2023 Peer-review started: February 21, 2023 First decision: March 21, 2023 Revised: March 24, 2023 Accepted: April 28, 2023 Article in press: April 28, 2023 Published online: June 27, 2023 Processing time: 111 Days and 7.4 Hours
Abstract
BACKGROUND
The case of Crohn's disease involving the duodenum is rare, and its surgical management requires a thorough understanding.
AIM
To investigate the surgical management of duodenal Crohn’s disease.
METHODS
We systematically reviewed patients diagnosed with duodenal Crohn's disease who underwent surgery in the Department of Geriatrics Surgery of the Second Xiangya Hospital of Central South University from January 1, 2004, to August 31, 2022. The general information, surgical procedures, prognosis, and other information of these patients were collected and summarized.
RESULTS
A total of 16 patients were diagnosed with duodenal Crohn’s disease, where 6 cases had primary duodenal Crohn’s disease, and 10 had secondary duodenal Crohn’s disease. Among patients with primary disease, 5 underwent duodenal bypass and gastrojejunostomy, and 1 received pancreaticoduodenectomy. Among those with a secondary disease, 6 underwent closure of duodenal defect and colectomy, 3 received duodenal lesion exclusion and right hemicolectomy, and 1 underwent duodenal lesion exclusion and double-lumen ileostomy.
CONCLUSION
Crohn's disease involving the duodenum is a rare condition. Different surgical management should be applied for patients with Crohn's disease presenting with different clinical manifestations.
Core Tip: Crohn's disease is a chronic, incurable inflammatory disease that affects the gastrointestinal tract function and causes extraintestinal complications. Crohn's disease involving the duodenum is a rare condition and different surgical management should be applied for patients with Crohn's disease presenting with different clinical manifestations. This study mainly summarized the surgical approaches and prognosis of 16 patients with duodenal Crohn's disease, thus providing some reference for the surgical management of the disease.
