Fiore M, Corrente A, Di Franco S, Alfieri A, Pace MC, Martora F, Petrou S, Mauriello C, Leone S. Antimicrobial approach of abdominal post-surgical infections. World J Gastrointest Surg 2023; 15(12): 2674-2692 [PMID: 38222012 DOI: 10.4240/wjgs.v15.i12.2674]
Corresponding Author of This Article
Marco Fiore, MD, Doctor, Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli,” Piazza Miraglia, 2, Naples 80138, Italy. marco.fiore@unicampania.it
Research Domain of This Article
Surgery
Article-Type of This Article
Review
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Dec 27, 2023; 15(12): 2674-2692 Published online Dec 27, 2023. doi: 10.4240/wjgs.v15.i12.2674
Antimicrobial approach of abdominal post-surgical infections
Marco Fiore, Antonio Corrente, Sveva Di Franco, Aniello Alfieri, Maria Caterina Pace, Francesca Martora, Stephen Petrou, Claudio Mauriello, Sebastiano Leone
Marco Fiore, Antonio Corrente, Sveva Di Franco, Aniello Alfieri, Maria Caterina Pace, Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli,” Naples 80138, Italy
Francesca Martora, Unit of Virology and Microbiology, “Umberto I” Hospital, Nocera Inferiore 84018, Italy
Stephen Petrou, Department of Emergency Medicine, University of California San Francisco, San Francisco, CA 94143, United States
Claudio Mauriello, Department of General Surgery, “Santa Maria delle Grazie” Hospital, Pozzuoli 80078, Italy
Sebastiano Leone, Division of Infectious Diseases, “San Giuseppe Moscati” Hospital, Avellino 83100, Italy
Author contributions: Fiore M and Leone S contributed to the writing of the main review; Fiore M, Corrente A, Di Franco S, and Alfieri A collected the data; Pace MC, Martora F, and Mauriello C supervised the writing of the paper; Petrou S revised and polished the language; All authors approved the final version to be published.
Conflict-of-interest statement: The authors have no conflicts of interest to declare.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marco Fiore, MD, Doctor, Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli,” Piazza Miraglia, 2, Naples 80138, Italy. marco.fiore@unicampania.it
Received: July 29, 2023 Peer-review started: July 29, 2023 First decision: September 14, 2023 Revised: October 24, 2023 Accepted: November 21, 2023 Article in press: November 21, 2023 Published online: December 27, 2023 Processing time: 151 Days and 6.3 Hours
Abstract
Abdominal surgical site infections (SSIs) are infections that occur after abdominal surgery. They can be superficial, involving the skin tissue only, or more profound, involving deeper skin tissues including organs and implanted materials. Currently, SSIs are large global health problem with an incidence that varies significantly depending on the United Nations’ Human Development Index. The purpose of this review is to provide a practical update on the latest available literature on SSIs, focusing on causative pathogens and treatment with an overview of the ongoing studies of new therapeutic strategies.
Core Tip: Abdominal surgical site infections (SSIs) are infections that occur after abdominal surgery. The knowledge of the site of infection and the probability of antibiotic resistance is fundamental to initiating appropriate empirical antibiotic treatment. The purpose of this review is to provide a practical update on the latest available literature on SSIs, focusing on causative pathogens and treatment with an overview of the ongoing studies of new therapeutic strategies.
