Letter to the Editor
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Apr 27, 2022; 14(4): 370-373
Published online Apr 27, 2022. doi: 10.4240/wjgs.v14.i4.370
Imaging of acute appendicitis: Advances
Sonay Aydın, Erdal Karavas, Düzgün Can Şenbil
Sonay Aydın, Erdal Karavas, Düzgün Can Şenbil, Department of Radiology, Erzincan Binali Yıldırım University Faculty of Medicine, Erzincan 24100, Turkey
Author contributions: Aydın S put forward the concept; Şenbil DC was responsible for designing; Karavas E provided resources; Aydın S and Karavas E were responsible for supervision, did the literature search and reviewed the manuscript critically; Şenbil DC and Aydın S were responsible for materials and wrote the manuscript; All authors have read and approved the final manuscript.
Conflict-of-interest statement: The authors declare having no conflicts of interest.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Düzgün Can Şenbil, MD, Academic Research, Doctor, Department of Radiology, Erzincan Binali Yıldırım University Faculty of Medicine, Başbağlar, Hacı Ali Akın Cd. No. 32 Erzincan 24100, Turkey. senbilcan@gmail.com
Received: December 3, 2021
Peer-review started: December 3, 2021
First decision: January 30, 2022
Revised: February 2, 2022
Accepted: March 26, 2022
Article in press: March 26, 2022
Published online: April 27, 2022
Abstract

We read with interest the review by Teng et al, who summarized the current approach to the diagnosis and treatment of acute appendicitis (AA). Also, the article summarizes the clinical scoring systems very effectively. In one of the previous studies conducted by our research group, we showed that the use of the Alvarado score, ultrasound and C-reactive protein values in combination provides a safe confirmation or exclusion of the diagnosis of AA. Computed tomography is particularly sensitive in detecting periappendiceal abscess, peritonitis and gangrenous changes. Computed tomography is not a good diagnostic tool in pediatric patients because of the ionizing radiation it produces. Ultrasound is a valuable diagnostic tool to differentiate AA from lymphoid hyperplasia. Presence of fluid collection in the periappendiceal and lamina propria thickness less than 1 mm are the most effective parameters in differentiating appendicitis from lymphoid hyperplasia. Although AA is the most common cause of surgical acute abdomen, it remains an important diagnostic and clinical challenge. By combining clinical scoring systems, laboratory data and appropriate imaging methods, diagnostic accuracy and adherence to treatment can be increased. Lymphoid hyperplasia and perforated appendicitis present significant diagnostic challenges in children. Additional ultrasound findings are increasingly defined to differentiate AA from these conditions.

Keywords: Acute appendicitis, Inflammation, Acute abdomen, Perforation

Core Tip: Despite the fact that acute appendicitis is the most common cause of acute abdomen, it remains a diagnostic and clinical challenge. When the ultrasound, Alvarado scoring and C-reactive protein are used in conjunction to diagnose acute appendicitis, the diagnosis can be safely confirmed or ruled out. Computed tomography scans are extremely sensitive in detecting complications from acute appendicitis. Computed tomography scans are especially effective at detecting periappendix abscesses, peritonitis and gangrenous changes. Because of the ionizing radiation it emits, computed tomography is not a good diagnostic tool in pediatric patients. In pediatric patients, ultrasound should be the preferred method.