Published online Dec 27, 2022. doi: 10.4240/wjgs.v14.i12.1350
Peer-review started: September 16, 2022
First decision: October 20, 2022
Revised: October 29, 2022
Accepted: December 6, 2022
Article in press: December 6, 2022
Published online: December 27, 2022
Processing time: 102 Days and 4.9 Hours
The only potential curative treatment for patients with pancreatic cancer is sur
To elucidate the associations of body composition measures derived from pre
One hundred fifteen patients undergoing pancreatic resection with curative intent for pancreatic cancer were retrospectively enrolled. A preoperative CT scan at the third lumbar vertebral level was performed to measure the skeletal muscle index (SMI), mean skeletal muscle radiodensity, subcutaneous adipose tissue index, and visceral to subcutaneous adipose tissue area ratio. The clinical and pathological data were collected. The effects of these factors on long-term survival were eva
Among the five body composition measures, only low SMI independently pre
Low preoperative SMI was more prevalent in elderly patients and was associated with a poor prognosis among pancreatic cancer patients, especially elderly patients.
Core Tip: Measures of body composition have been regarded as a reliable prognostic predictor for cancer patients after surgery, but further research is needed. In this study, we showed that low preoperative skeletal muscle index (SMI) potentially predicts the prognosis of pancreatic cancer patients. We also revealed that low SMI was more prevalent in elderly patients and was associated with a poor prognosis among elderly patients after pancreatic cancer resection.