Xia K, Gao RY, Wu XC, Yin L, Chen CQ. Timing of individualized surgical intervention in Crohn’s disease . World J Gastrointest Surg 2022; 14(12): 1320-1328 [PMID: 36632120 DOI: 10.4240/wjgs.v14.i12.1320]
Corresponding Author of This Article
Chun-Qiu Chen, Doctor, Chief Doctor, Professor, Diagnostic and Treatment Center for Refractory Diseases of Abdomen Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, No. 301 Yanchang Middle Road, Shanghai 200072, China. chenchunqiu6@126.com
Research Domain of This Article
Surgery
Article-Type of This Article
Minireviews
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Dec 27, 2022; 14(12): 1320-1328 Published online Dec 27, 2022. doi: 10.4240/wjgs.v14.i12.1320
Timing of individualized surgical intervention in Crohn’s disease
Kai Xia, Ren-Yuan Gao, Xiao-Cai Wu, Lu Yin, Chun-Qiu Chen
Kai Xia, Ren-Yuan Gao, Xiao-Cai Wu, Lu Yin, Chun-Qiu Chen, Diagnostic and Treatment Center for Refractory Diseases of Abdomen Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai 200072, China
Author contributions: Xia K drafted the manuscript, and collected and organized the literature; Gao RY, Wu XC, Yin L, and Chen CQ contributed to manuscript modification.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Chun-Qiu Chen, Doctor, Chief Doctor, Professor, Diagnostic and Treatment Center for Refractory Diseases of Abdomen Surgery, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, No. 301 Yanchang Middle Road, Shanghai 200072, China. chenchunqiu6@126.com
Received: September 1, 2022 Peer-review started: September 1, 2022 First decision: October 20, 2022 Revised: October 24, 2022 Accepted: December 1, 2022 Article in press: December 1, 2022 Published online: December 27, 2022 Processing time: 116 Days and 22.9 Hours
Abstract
Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with an increasing incidence worldwide. Comprehensive therapy for CD focuses on symptom control and healing the intestinal mucosa to improve the quality of life and prevent complications. Surgical intervention plays a vital role in comprehensive therapy. However, deciding the optimal timing for surgical intervention has long been a focus of controversy. This review provides insights into the timing of surgery for CD and guides clinicians in daily treatment.
Core Tip: Surgical intervention plays an important role in the comprehensive treatment of Crohn’s disease (CD). However, the timing of surgery has always been a major controversial point. This review focuses on the main surgical indications for CD and the clinical factors that may influence surgical timing decisions. We also emphasize the value of early surgery in treating CD.