Mamaghanian A, Shamshirgaran SM, Aiminisani N, Aliasgarzadeh A. Clinico-epidemiological factors of health related quality of life among people with type 2 diabetes. World J Diabetes 2017; 8(8): 407-413 [PMID: 28861178 DOI: 10.4239/wjd.v8.i8.407]
Corresponding Author of This Article
Seyed Morteza Shamshirgaran, MD, PhD, Assistant Professor, Department of Statistics and Epidemiology, School of Health Sciences Tabriz University of Medical Sciences, Rm 405, Golgasht Ave., Atar Neyshabouri St, Tabriz 5165665931, Iran. shamshirgaranm@tbzmed.ac.ir
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Observational Study
Open-Access Policy of This Article
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Table 2 The status of different domains of health related quality of life according to the gender of diabetic people referring to diabetes clinics of Tabriz, 2015
HRQOL dimensions
Total
Male
Female
P-value
Mean
SD
Mean
SD
Mean
SD
Physical health
51.24
13.34
54.97
12.92
49.34
13.18
< 0.001
Psychological health
60.38
14.54
65.26
13.30
57.88
14.54
< 0.001
Social relationship
38.32
16.74
41.96
16.71
36.46
16.48
0.002
Environmental
58.48
10.48
59.64
11.13
57.88
10.10
0.115
Total HRQOL score
52.11
11.53
55.46
11.34
50.39
11.27
< 0.001
Table 3 Different dimensions of health related quality of life according to the clinical aspects of diabetes among diabetic people referring to diabetes clinics of Tabriz, 2015
Variable
Subgroups
n (%)
Physical health
Social relationship
Environmental
Psychological health
Total HRQOL
Gender
Male
134 (34)
54.97 (12.92)
41.96 (16.71)
59.65 (11.14)
65.26 (13.30)
55.46 (11.34)
Female
260 (66)
49.34 (13.18)
36.46 (16.48)
57.88 (10.11)
57.88 (14.54)
50.39 (11.27)
P-value
-
< 0.001
0.002
0.115
< 0.001
< 0.001
Age
≤ 49
85 (21.6)
58.65 (11.64)
47.8 (17.59)
61.64 (11.14)
64.11 (16.15)
58.8 (11.66)
59-50
147 (37.3)
52.36 (12.97)
39.68 (15.17)
59.71 (10.9)
61.37 (14.71)
53.28 (11.19)
≥ 60
162 (41.1)
46.32 (12.53)
32.08 (15.02)
55.68 (9.01)
57.5 (12.91)
47.89 (10.11)
P-value
-
< 0.001
< 0.001
< 0.001
0.002
< 0.001
Education
Illiterate
143 (36.3)
44.56 (11.04)
29.8 (13.21)
54.34 (8.57)
55.06 (12.25)
45.94 (8.73)
Primary school
149 (37.8)
51.99 (12.93)
40.25 (16.08)
57.46 (10.13)
59.79 (14.31)
52.37 (10.87)
Secondary school and higher
102 (25.9)
59.61 (11.92)
47.55 (16.52)
65.83 (9.7)
68.77 (14.15)
60.44 (10.68)
P-value
-
< 0.001
< 0.001
< 0.001
< 0.001
< 0.001
Income
Low (< 1000)
224 (56.8)
48.43 (12.82)
35.44 (17.47)
56.22 (9.98)
57.9 (14.73)
49.50 (11.39)
acceptable
170 (43.2)
54.23 (13.27)
41.38 (15.41)
60.86 (10.49)
63 (13.9)
54.86 (11.06)
P-value
-
< 0.001
< 0.001
< 0.001
< 0.001
< 0.001
Disease duration (yr)
≥ 3 yr
51 (12.9)
56.12 (13.81)
41.88 (16.86)
61.7 (12.31)
65.48 (14.81)
56.29 (12.18)
4-7
93 (23.6)
51.09 (10.95)
37.3 (16.15)
57.52 (9.29)
59.47 (12.48)
51.34 (10.06)
≤ 7 yr
250 (63.5)
50.33 (13.89)
38 (16.91)
58.19 (10.43)
59.7 (15.03)
51.55 (11.78)
P-value
-
0.019
0.26
0.058
0.029
< 0.001
< 25
72 (20.2)
55.21 (12.90)
42.08 (17.32)
60.77 (12.09)
64.36 (15.85)
55.6 (12.53)
25-29.9
148 (41.6)
54.2 (13.01)
39.25 (15.68)
59.2 (10.26)
62.15 (14.22)
53.7 (11.66)
≥ 30
136 (38.2)
47.97 (12.85)
35.27 (17.46)
57.16 (9.98)
58.23 (13.79)
49.66 (11.08)
P-value
-
< 0.001
0.014
0.052
0.008
0.001
HbA1c
< 7
180 (47.2)
51.11 (12.70)
38.02 (16.02)
57.8 (10.84)
60.1 (14.12)
51.76 (11.07)
≥ 7
201 (52.8)
51.21 (14.01)
37.96 (17.35)
58.89 (10.25)
60.83 (14.75)
52.22 (12.05)
P-value
-
0.938
0.969
0.136
0.62
0.696
NORMAL
195 (49.6)
53.83 (10.78)
38.33 (15.11)
60.4 (9.57)
64.73 (11.81)
54.32 (9.74)
Kessler psychological distress
MILD
72 (18.3)
52.01 (13.65)
41.97 (18.03)
57.47 (10.25)
60.84 (12.61)
53.07 (11.57)
MODERATE
52 (2.13)
50.96 (14.41)
39.19 (19.07)
58.57 (12.12)
59.76 (16.61)
52.12 (13.91)
SEVER
74 (18.8)
43.9 (15.76)
34.14 (17.23)
54.33 (66.10)
48.87 (15.22)
45.31 (11.66)
P-value
-
< 0.001
0.042
< 0.001
< 0.001
< 0.001
Functional limitation
No
106 (26.9)
61.25 (10.89)
47.47 (15.85)
63.05 (11.16)
67.91 (14.37)
59.92 (10.79)
Moderate
78 (19.8)
54.92 (11.51)
44.34 (18.16)
61.12 (9.62)
64.79 (12.13)
56.29 (10.18)
Sever
210 (53.3)
44.8 (11.35)
31.44 (13.25)
55.17 (9.26)
54.91 (13.17)
46.58 (9.23)
P-value
-
< 0.001
< 0.001
< 0.001
< 0.001
< 0.001
Treatment
Oral medication
223 (57.4)
53.57 (12.59)
38.69 (15.71)
58.97 (10.37)
61.69 (14.64)
53.11 (11.09)
Oral medication + insulin injection
164 (42.2)
48.92 (13.64)
37.82 (17.96)
58.07 (10.55)
58.78 (14.38)
50.9 (11.97)
P-value
-
0.007
0.883
0.161
0.101
0.12
Comorbidities
No
102 (25.9)
58.93 (11.79)
42.23 (18.29)
63.37 (10.57)
66.51 (14.82)
57.76 (11.75)
1
207 (52.5)
50.82 (12.07)
38.28 (16.42)
57.56 (10.03)
60.49 (13.19)
51.79 (10.66)
≥ 2
85 (21.6)
43.05 (12.99)
33.74 (14.41)
54.83 (9.39)
52.75 (13.88)
46.09 (10.09)
P-value
-
< 0.001
0.002
< 0.001
< 0.001
< 0.001
Table 4 Multivariate linear regression models of significant factors predicting health related quality of life domains among diabetic people referring to diabetes clinics of Tabriz, 2015
HRQOL domains
Variables
B (SE)
Beta
P-value
95%CI of B
Adjusted R2
Lower
Upper
Physical health
Education
3.35 (0.83)
0.198
< 0.001
1.77
4.93
0.436
BMI
-1.55 (0.75)
-0.087
0.039
-3.12
0.07
Functional limitation
-4.79 (0.77)
-0.229
< 0.001
-6.11
-3.07
Kessler psychological distress
-1.98 (0.46)
-0.174
< 0.001
-2.90
-1.06
Comorbidies
-4.05 (0.85)
-0.210
< 0.001
-5.73
-2.37
Social relationship
Age
-4.65 (1.2)
-0.212
< 0.001
-7.01
-2.28
0.279
Education
5.3 (1.15)
0.246
< 0.001
3.03
7.56
Functional limitation
-4.05 (1.11)
-0.208
< 0.001
-6.24
-1.87
Psychological health
Education
3.52 (0.94)
0.190
< 0.001
1.67
5.38
0.353
Functional limitation
-3.94 (0.9)
-0.234
< 0.001
-5.72
-2.15
Comorbidies
-3.72 (1.0)
-0.176
< 0.001
-5.69
-1.75
Kessler psychological distress
-3.96 (0.55)
-0.317
< 0.001
-5.04
-2.88
Environment
Education
4.3 (0.73)
0.318
< 0.001
2.86
5.75
0.257
Comorbidies
-2.37 (0.78)
-0.154
0.003
-3.91
-0.83
Kessler psychological distress
-1.33 (0.43)
-0.135
0.004
-2.07
-0.38
Functional limitation
-1.77 (0.7)
-0.145
0.012
-3.17
-0.38
Income
2.13 (1.02)
0.101
0.037
0.12
4.14
Total HRQOL score
Education
4.12 (0.7)
0.278
< 0.001
2.73
5.5
0.433
Functional limitation
-3.59 (0.67)
-0.267
< 0.001
-4.92
-2.26
Age
1.48 (0.73)
-0.098
0.044
-2.93
-0.03
Kessler psychological distress
-2.02 (0.41)
-0.203
< 0.001
2.83
-1.21
Income
1.98 (0.97)
0.085
0.044
0.05
3.9
Comorbidities
-2.41 (0.75)
-0.143
0.001
-3.89
-9.41
Citation: Mamaghanian A, Shamshirgaran SM, Aiminisani N, Aliasgarzadeh A. Clinico-epidemiological factors of health related quality of life among people with type 2 diabetes. World J Diabetes 2017; 8(8): 407-413