Observational Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Aug 15, 2017; 8(8): 407-413
Published online Aug 15, 2017. doi: 10.4239/wjd.v8.i8.407
Clinico-epidemiological factors of health related quality of life among people with type 2 diabetes
Azra Mamaghanian, Seyed Morteza Shamshirgaran, Nayyereh Aiminisani, Akbar Aliasgarzadeh
Azra Mamaghanian, Seyed Morteza Shamshirgaran, Nayyereh Aiminisani, Department of Statistics and Epidemiology, School of Health Sciences Tabriz University of Medical Sciences, Tabriz 5165665931, Iran
Seyed Morteza Shamshirgaran, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz 5165665931, Iran
Akbar Aliasgarzadeh, Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz 5165665931, Iran
Author contributions: All authors were involved in design of the study; Mamaghanian A was responsible for collection and assembly of data and contributed to data analysis; Shamshirgaran SM was responsible for provision of study material and drafted the manuscript; Shamshirgaran SM, Aiminisani N and Aliasgarzadeh A supervised and supported data collection and analysis; all authors read and approved the manuscript including the final version.
Supported by Research Council, Faculty of Health Sciences, Tabriz University of Medical Sciences grant, No. 5.53.1590.
Institutional review board statement: The study was reviewed and approved by the ethics committee of Tabriz University of Medical Sciences (TBZMED.REC.2015.55).
Informed consent statement: All patients completed an informed consent form prior to the interview session.
Conflict-of-interest statement: There are no conflicts of interest to report.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Seyed Morteza Shamshirgaran, MD, PhD, Assistant Professor, Department of Statistics and Epidemiology, School of Health Sciences Tabriz University of Medical Sciences, Rm 405, Golgasht Ave., Atar Neyshabouri St, Tabriz 5165665931, Iran. shamshirgaranm@tbzmed.ac.ir
Telephone: +98-33-57582 Fax: +98-33-57582
Received: January 25, 2017
Peer-review started: February 6, 2017
First decision: March 28, 2017
Revised: May 9, 2017
Accepted: May 18, 2017
Article in press: May 19, 2017
Published online: August 15, 2017
Processing time: 197 Days and 10.9 Hours
Abstract
AIM

To investigate the quality of life (QOL) and its clinical and epidemiological correlates among people with type 2 diabetes.

METHODS

This cross-sectional study was conducted in Tabriz, Northwest of Iran, including a total of 394 people with type 2 diabetes using convenient sampling method from November 2014 to March 2015. General information including demographic, socioeconomic status and lifestyle factors were collected by trained interviewers. Clinical information was retrieved from clinic’s record and QOL was assessed using the 26-item WHOQOL-BRIFE questionnaire. Univariate and multivariate linear regression were performed to assess the related factors and QOL dimensions.

RESULTS

The mean of overall health related QOL was 52.11 ± 11.53 and the maximum and minimum dimensions were respectively seen in psychological (60.38 ± 14.54) and social (38.32 ± 16.94) dimensions. The results of multiple linear regression showed a significant overall relationship between HRQOL and age (b = -1.48%, 95%CI: -0.03 and -2.93) level of education (b = 4.12%, 95%CI: 2.73 and 5.5), number of comorbidities (b = -2.41%, 95%CI: -3.89 and -9.41), and level of income (b = 1.98, 95%CI: 0.05 and 3.9), functional limitation (b = -3.59, 95%CI: -2.26 and -4.92) and psychological distress (b = -2.02%, 95%CI: -2.83 and -1.21). Level of education, functional limitation, psychological distress were associated with the score of physical, mental and environmental dimensions, and number of comorbidities was associated with the score of physical and mental dimensions.

CONCLUSION

Based on our findings, lifestyle modification and increasing facilities of clinics providing service can be effective steps to improve the QOL among people with type 2 diabetes.

Keywords: Diabetes mellitus; Type 2; Lifestyle; Quality of life; Psychological distress

Core tip: Health related quality of life (HRQOL) is an important outcome measure in chronic diseases. The aim of this study was to assess quality of life and a range of epidemiological and clinical factors among people with type 2 diabetes. The findings of the present study showed that age, level of education, income, body mass index, functional limitation, psychological distress and number of comorbidities have a decisive role on HRQOL of patients with type 2 diabetes. So, it is important to improve the HRQOL by considering above predictors as an appropriate mechanism for public health interventions for type 2 diabetes.