Role of antidiabetic agents in type 2 diabetes patients with chronic kidney disease

doi:10.4239/wjd.v14.i4.352

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Apr 15, 2023 (publication date) through Nov 28, 2024

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Apr 15, 2023; 14(4): 352-363
Published online Apr 15, 2023. doi: 10.4239/wjd.v14.i4.352

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Figure 1 Insulin signaling pathway and inflammation and oxidative stress in insulin resistance. IRS-1: Insulin receptor substrate-1; PI3K: Phosphatidyl-inositol-3-kinase (PI3K); PIP3: Phosphatidylinositol-triphosphate; PKB/Akt: Protein kinase B/Akt pathway; GLUT4: Glucose transporter 4 (GLUT4): FFA: Free fatty acids; TNF-α: Tumor necrosis factor alfa; IL-6: Interleukin-6; SOSC-3: Suppressor of cytokine signaling-3 pathway; ROS: Reactive oxygen species; JNK1: C-Jun N-terminal kinase 1; Nrf2: Nuclear factor-erythroid-2-related factor-2.

Citation: Lin WR, Liu KH, Ling TC, Wang MC, Lin WH. Role of antidiabetic agents in type 2 diabetes patients with chronic kidney disease. World J Diabetes 2023; 14(4): 352-363
URL: https://www.wjgnet.com/1948-9358/full/v14/i4/352.htm
DOI: https://dx.doi.org/10.4239/wjd.v14.i4.352