Review
Copyright ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 15, 2023; 14(4): 352-363
Published online Apr 15, 2023. doi: 10.4239/wjd.v14.i4.352
Role of antidiabetic agents in type 2 diabetes patients with chronic kidney disease
Wei-Ren Lin, Kuan-Hung Liu, Tsai-Chieh Ling, Ming-Cheng Wang, Wei-Hung Lin
Wei-Ren Lin, Kuan-Hung Liu, Tsai-Chieh Ling, Ming-Cheng Wang, Wei-Hung Lin, Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, Tainan 704, Taiwan
Author contributions: Lin WR wrote the paper; Liu KH, Ling TC, Wang MC and Lin WH edited and revised manuscript; and all authors have read and approved the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wei-Hung Lin, MD, PhD, Associate Professor, Doctor, Staff Physician, Division of Nephrology, Department of Internal Medicine, National Cheng Kung University Hospital, No. 138 Sheng-Li Road, Tainan 704, Taiwan. dindonwhlin@hotmail.com
Received: November 27, 2022
Peer-review started: November 27, 2022
First decision: December 26, 2022
Revised: January 10, 2023
Accepted: April 4, 2023
Article in press: April 4, 2023
Published online: April 15, 2023
Processing time: 136 Days and 2 Hours
Core Tip

Core Tip: Insulin resistance is the main cause of type 2 diabetes mellitus and is associated with cardiovascular events. It is also common in chronic kidney disease patients. We discuss the mechanisms of insulin resistance in such patients and the interaction of currently available anti-diabetic medications with insulin resistance.