Gut dysbiosis, low-grade inflammation, and renal impairment severity in elderly diabetic nephropathy

Figure 1 Correlations of gut microbiota with renal, metabolic and inflammatory indices. ^aP < 0.05. A: Correlation matrix between intestinal microbial structure and renal function level; B: Correlation analysis matrix between changes in glucose and lipid metabolism and changes in gut microbiota; C: Correlation analysis matrix between changes in inflammation and renal function indicators and changes in gut microbiota. eGFR: Estimated glomerular filtration rate; Cys-C: Cystatin C; Scr: Serum creatinine; BUN: Blood urea nitrogen; ACR: Albumin-to-creatinine ratio; FBG: Fasting blood glucose; PBG: Postprandial blood glucose; HbA1c: Glycated hemoglobin; FINS: Fasting insulin; HOMA-IR: Homeostasis model assessment of insulin resistance; TC: Total cholesterol; TG: Triglycerides; LDL-C: Low-density lipoprotein cholesterol; HDL-C: High-density lipoprotein cholesterol; FFA: Free fatty acids; CRP: C-reactive protein; TNF-α: Tumor necrosis factor α; IL: Interleukin.