Systematic Reviews
Copyright ©The Author(s) 2023.
World J Diabetes. Jun 15, 2023; 14(6): 919-929
Published online Jun 15, 2023. doi: 10.4239/wjd.v14.i6.919
Figure 1
Figure 1 Systematic representation of metabolic pathways affected by hyperglycaemic and oxidative stress. Hyperglycaemia causes cell damage in three ways: (1) By directly increasing oxidative stress which affects glycolytic enzymes; (2) by forming advanced glycation end products which activate NF-κβ and increase DNA damage; and (3) by affecting diacylglycerol enzyme and ultimately reducing nitric oxide levels.
Figure 2
Figure 2 Flow chart of study selection process. Created from: https://prisma-statement.org/prismastatement/flowdiagram.aspx.