Retrospective Cohort Study
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Sep 15, 2017; 8(9): 429-435
Published online Sep 15, 2017. doi: 10.4239/wjd.v8.i9.429
Clinical profile of diabetes at diagnosis among children and adolescents at an endocrine clinic in Ghana
Emmanuel Ameyaw, Serwah B Asafo-Agyei, Sumithira Thavapalan, Angela C Middlehurst, Graham D Ogle
Emmanuel Ameyaw, Serwah B Asafo-Agyei, Department of Child Health, Komfo Anokye Teaching Hospital, P.O. Box 1934, Kumasi, Ghana
Sumithira Thavapalan, Angela C Middlehurst, Graham D Ogle, International Diabetes Federation Life for a Child Program, Glebe, NSW 2037, Australia
Sumithira Thavapalan, Angela C Middlehurst, Graham D Ogle, Diabetes NSW, Glebe, NSW 2037, Australia
Author contributions: Ameyaw E contributed to study design, conducted the study, and contributed to the manuscript; Asafo-Agyei SB contributed to concept and assisted in conduct of the study; Thavapalan S analysed the data, prepared the figures, and reviewed the manuscript; Middlehurst AC assisted with study design and review of data; Ogle GD designed the study, interpreted the results, and was the lead writer on the manuscript.
Institutional review board statement: The study was reviewed and approved by the Committee on Human Research Publication and Ethics, School of Medical Sciences/Komfo Anokye Teaching Hospital, College of Health Sciences, Kwame Nkrumah University of Science and Technology.
Informed consent statement: All subjects gave informed consent.
Conflict-of-interest statement: None of the authors have any conflicts of interest in regards to this study.
Data sharing statement: Not relevant.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr.Graham D Ogle, International Diabetes Federation Life for a Child Program, 26 Arundel St., Glebe, NSW 2037, Australia. grahamo@diabetesnsw.com.au
Telephone: +61-95-529922
Received: January 25, 2017
Peer-review started: January 28, 2017
First decision: May 11, 2017
Revised: May 31, 2017
Accepted: June 19, 2017
Article in press: June 20, 2017
Published online: September 15, 2017
Processing time: 230 Days and 10.5 Hours
Core Tip

Core tip: In this study of 106 consecutive new diagnoses of diabetes in young people < 20 years in a tertiary referral centre in Ghana, type 1 predominated (85%) with the remaining cases clinically diagnosed as type 2. Both types had a female preponderance. Type 1 peak age of onset was 12-13 years. All type 2 subjects had acanthosis nigricans. Most presented in ketoacidosis signifying a lack of awareness of presentation features. Clinic numbers quickly rose due to availability of supplies and expertise. Further typology studies are indicated to further define diabetes type.