Review
Copyright ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2017; 8(6): 235-248
Published online Jun 15, 2017. doi: 10.4239/wjd.v8.i6.235
Diabetes mellitus and stroke: A clinical update
Nyo Nyo Tun, Ganesan Arunagirinathan, Sunil K Munshi, Joseph M Pappachan
Nyo Nyo Tun, Ganesan Arunagirinathan, Department of Endocrinology and Diabetes, Western General Hospital, NHS Lothian, Edinburgh EH4 2XU, United Kingdom
Sunil K Munshi, Department of Stroke Medicine, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG5 1PB, United Kingdom
Joseph M Pappachan, Department of Endocrinology and Diabetes, Royal Lancaster Infirmary, University Hospitals Morecambe NHS Trust, Lancaster LA1 4RP, United Kingdom
Author contributions: Munshi SK and Pappachan JM conceived the idea; Tun NN did the initial draft of the paper that was further modified by Arunagirinathan G, Munshi SK and Pappachan JM; all authors contributed to literature search and modification and revision of the paper in the final form; Pappachan JM is the guarantor of the work and takes responsibility of the accuracy of the paper.
Conflict-of-interest statement: None.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Dr. Joseph M Pappachan, MD, MRCP, Consultant in Endocrinology and Diabetes, Department of Endocrinology and Diabetes, Royal Lancaster Infirmary, University Hospitals Morecambe NHS Trust, Ashton Road, Lancaster LA1 4RP, United Kingdom. drpappachan@yahoo.co.in
Telephone: +44-1524-512482 Fax: +44-1524-583447
Received: December 31, 2016
Peer-review started: January 5, 2017
First decision: February 20, 2017
Revised: March 27, 2017
Accepted: May 3, 2017
Article in press: May 5, 2017
Published online: June 15, 2017
Processing time: 165 Days and 2.2 Hours
Core Tip

Core tip: With the current global prevalence of more than 415 million, diabetes mellitus (DM) poses very high risk for cardiovascular diseases including stroke. Associated risk factors for stroke such as obesity, hypertension and dyslipidaemia are also high among DM cases especially in those with type 2 diabetes that further increases stroke risk. Thorough understanding of the epidemiology, pathophysiology and management options for patients with DM and co-morbidities is imperative for a rational medical practice among healthcare professionals. This review updates a scientific approach to patients with diabetes and stroke.