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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Apr 10, 2016; 7(7): 142-152
Published online Apr 10, 2016. doi: 10.4239/wjd.v7.i7.142
Published online Apr 10, 2016. doi: 10.4239/wjd.v7.i7.142
Novel nutraceutic therapies for the treatment of metabolic syndrome
Esperanza Martínez-Abundis, Miriam Mendez-del Villar, Karina G Pérez-Rubio, Laura Y Zuñiga, Marisol Cortez-Navarrete, Alejandra Ramírez-Rodriguez, Manuel González-Ortiz, Institute of Experimental and Clinical Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Guadalajara 44340, Jalisco, Mexico
Author contributions: All authors contributed to design the study, obtain data, and write, review and edit the manuscript.
Conflict-of-interest statement: Authors declare no conflict of interest with regard to this manuscript.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Manuel González-Ortiz, MD, MSc, PhD, Institute of Experimental and Clinical Therapeutics, Department of Physiology, Health Sciences University Center, University of Guadalajara, Montes Urales 1409, Colonia Independencia, Guadalajara 44340, Jalisco, Mexico. uiec@prodigy.net.mx
Telephone: +52-33-38267022 Fax: +52-33-36161218
Received: August 26, 2015
Peer-review started: August 30, 2015
First decision: September 28, 2015
Revised: January 24, 2016
Accepted: February 14, 2016
Article in press: February 16, 2016
Published online: April 10, 2016
Processing time: 224 Days and 5.9 Hours
Peer-review started: August 30, 2015
First decision: September 28, 2015
Revised: January 24, 2016
Accepted: February 14, 2016
Article in press: February 16, 2016
Published online: April 10, 2016
Processing time: 224 Days and 5.9 Hours
Core Tip
Core tip: Metabolic syndrome (MetS) is a cluster of endocrine problems including obesity, dysglycemia, dyslipidemia, and hypertension. Unfortunately, there is no unique treatment to control it. Nutraceutic therapies such as berberine, bitter melon, Gymnema sylvestre, Irvingia gabonensis, resveratrol and ursolic acid have demonstrated some improvement in anthropometric parameters and cardiometabolic risk factors and could be considered as treatment for patients with MetS. This review attempts to demonstrate the beneficial effects and limitations of some of these novel nutraceutic therapies.