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©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 25, 2016; 7(12): 252-259
Published online Jun 25, 2016. doi: 10.4239/wjd.v7.i12.252
Published online Jun 25, 2016. doi: 10.4239/wjd.v7.i12.252
Does parity worsen diabetes-related chronic complications in women with type 1 diabetes?
Marilia Brito Gomes, Ana Almeida, Department of Internal Medicine, Diabetes Unit, State University of Rio de Janeiro, Rio de Janeiro 20550-900, Brazil
Carlos Antonio Negrato, Bauru’s Diabetics Association, Bauru, São Paulo 17012-433, Brazil
Antonio Ponce de Leon, Department of Epidemiology, State University of Rio de Janeiro, Rio de Janeiro 20550-900, Brazil
Author contributions: Gomes MB, Negrato CA, Almeida A and de Leon AP analyzed the data and wrote the manuscript; Almeida A collected the data.
Supported by The Farmanguinhos/Fundação Oswaldo Cruz/National Health Ministry, Brazilian Diabetes Society, Fundação do Amparo à Pesquisa do Estado do Rio de Janeiro, and Conselho Nacional de Desenvolvimento Científico e Tecnológico do Brasil, No. 563753/2010-2.
Institutional review board statement: The study was reviewed and approved by the State University of Rio de Janeiro Institutional Review Board and Bauru’s Diabetics Association Institutional Review Board.
Informed consent statement: All study participants or their legal guardian provided informed written consent about personal and medical data collection prior to study enrolment.
Conflict-of-interest statement: The authors declare that they have no conflict of interests to disclose.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Carlos Antonio Negrato, MD, PhD, Bauru’s Diabetics Association, Rua Saint Martin 27-07, Bauru, São Paulo 17012-433, Brazil. carlosnegrato@uol.com.br
Telephone: +55-14-32348915 Fax: +55-14-32348915
Received: December 15, 2015
Peer-review started: December 18, 2015
First decision: February 29, 2016
Revised: March 31, 2016
Accepted: May 7, 2016
Article in press: May 9, 2016
Published online: June 25, 2016
Processing time: 183 Days and 18.8 Hours
Peer-review started: December 18, 2015
First decision: February 29, 2016
Revised: March 31, 2016
Accepted: May 7, 2016
Article in press: May 9, 2016
Published online: June 25, 2016
Processing time: 183 Days and 18.8 Hours
Core Tip
Core tip: To the best of our knowledge, this was the largest study ever conducted with pregnant women with type 1 diabetes in Brazil and maybe in Latin America. Our results suggest that parity did not have an important effect upon hypertension and micro or macrovascular diabetes-related chronic complications. Further prospective studies with a larger number of patients must be addressed to clarify the relationship between parity, appearance or worsening of diabetes-related chronic complications.