Type 2 diabetes is associated with a worse functional outcome of ischemic stroke

doi:10.4239/wjd.v5.i6.939

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Original Article

World J Diabetes. Dec 15, 2014; 5(6): 939-944
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.939

Type 2 diabetes is associated with a worse functional outcome of ischemic stroke

Konstantinos Tziomalos, Marianna Spanou, Stella D Bouziana, Maria Papadopoulou, Vasilios Giampatzis, Stavroula Kostaki, Vasiliki Dourliou, Maria Tsopozidi, Christos Savopoulos, Apostolos I Hatzitolios, First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 54636 Thessaloniki, Greece

Author contributions: Tziomalos K and Hatzitolios AI designed the research; Tziomalos K, Spanou M, Bouziana SD, Papadopoulou M, Giampatzis V, Kostaki S, Dourliou V, Tsopozidi M, Savopoulos C and Hatzitolios AI performed the research; Tziomalos K analyzed the data; Tziomalos K, Spanou M and Hatzitolios AI wrote the paper.

Correspondence to: Konstantinos Tziomalos, MD, PhD, First Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 54636 Thessaloniki, Greece. ktziomalos@yahoo.com

Telephone: +30-2310-994621 Fax: +30-2310-994773

Received: April 18, 2014
Revised: July 2, 2014
Accepted: July 25, 2014
Published online: December 15, 2014
Processing time: 239 Days and 1.8 Hours

Core Tip

Core tip: Even though type 2 diabetes mellitus (T2DM) is a major independent risk factor for ischemic stroke, it is unclear whether stroke severity and functional outcome differs between diabetic and non-diabetic patients. In the present study, T2DM was associated with worse functional outcome at discharge despite similar stroke severity at admission. The detrimental effect of T2DM on functional outcome was independent of the increased prevalence of cardiovascular risk factors in diabetic patients.