Linking uric acid metabolism to diabetic complications

doi:10.4239/wjd.v5.i6.787

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Diabetes. Dec 15, 2014; 5(6): 787-795
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.787

Linking uric acid metabolism to diabetic complications

Akifumi Kushiyama, Kentaro Tanaka, Shigeko Hara, Shoji Kawazu

Akifumi Kushiyama, Kentaro Tanaka, Shigeko Hara, Shoji Kawazu, Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, 2-2-6, Tokyo 103-0002, Japan

Author contributions: All authors contributed to this work.

Correspondence to: Akifumi Kushiyama, MD, PhD, Assistant Division Chief, Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, 2-2-6, Nihonbashi Bakurocho, Chuo-ku, Tokyo 103-0002, Japan. kusiyaa-tky@umin.ac.jp

Telephone: +81-3-36395501 Fax: +81-3-36395520

Received: August 31, 2014
Revised: October 22, 2014
Accepted: November 7, 2014
Published online: December 15, 2014
Processing time: 103 Days and 23.3 Hours

Core Tip

Core tip: Uric acid (UA) is derived from essential metabolism, and UA metabolism is becoming a novel risk and interventional factor of lifestyle-related diseases in this obesity-prone era. The relationship between UA metabolism and diabetic complications is highlighted in this review and supposed molecular mechanisms are mentioned.