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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Dec 15, 2014; 5(6): 787-795
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.787
Published online Dec 15, 2014. doi: 10.4239/wjd.v5.i6.787
Linking uric acid metabolism to diabetic complications
Akifumi Kushiyama, Kentaro Tanaka, Shigeko Hara, Shoji Kawazu, Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, 2-2-6, Tokyo 103-0002, Japan
Author contributions: All authors contributed to this work.
Correspondence to: Akifumi Kushiyama, MD, PhD, Assistant Division Chief, Division of Diabetes and Metabolism, The Institute for Adult Diseases, Asahi Life Foundation, 2-2-6, Nihonbashi Bakurocho, Chuo-ku, Tokyo 103-0002, Japan. kusiyaa-tky@umin.ac.jp
Telephone: +81-3-36395501 Fax: +81-3-36395520
Received: August 31, 2014
Revised: October 22, 2014
Accepted: November 7, 2014
Published online: December 15, 2014
Processing time: 103 Days and 23.3 Hours
Revised: October 22, 2014
Accepted: November 7, 2014
Published online: December 15, 2014
Processing time: 103 Days and 23.3 Hours
Core Tip
Core tip: Uric acid (UA) is derived from essential metabolism, and UA metabolism is becoming a novel risk and interventional factor of lifestyle-related diseases in this obesity-prone era. The relationship between UA metabolism and diabetic complications is highlighted in this review and supposed molecular mechanisms are mentioned.