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World J Diabetes. Oct 15, 2014; 5(5): 689-696
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.689
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.689
Advances in management of type 1 diabetes mellitus
Ravindranath Aathira, Vandana Jain, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India
Author contributions: Aathira R did the literature search and reviewed the relevant articles to contruct the body of the document; Jain V guided through the whole process and edited the final document.
Correspondence to: Vandana Jain, Additional Professor, Department of Pediatrics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. drvandanajain@gmail.com
Telephone: +91-981-0167265 Fax: +91-011-26588663
Received: May 13, 2014
Revised: June 18, 2014
Accepted: July 17, 2014
Published online: October 15, 2014
Revised: June 18, 2014
Accepted: July 17, 2014
Published online: October 15, 2014
Core Tip
Core tip: As therapy of type 1 diabetes poses important challenges because of life long insulin dependence,multiple injections, excursions in glucose values and inability to simulate the pancreas, newer modalities of therapy are emerging. Hence, this is the right time to review developments in this front. This review conjures up recent advances in continuous glucose monitors, closed loop systems, insulin analogues, insulin gene therapy, transplantation and immunological vaccination.