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World J Diabetes. Oct 15, 2014; 5(5): 577-585
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.577
Published online Oct 15, 2014. doi: 10.4239/wjd.v5.i5.577
Peripheral arterial disease, type 2 diabetes and postprandial lipidaemia: Is there a link?
Pedro Valdivielso, José Ramírez-Bollero, Carmen Pérez-López, UGC de Medicina Interna, Hospital “Virgen de la Victoria” de Málaga y Departamento de Medicina y Dermatología, Universidad de Málaga, 29010 Málaga, Spain
Author contributions: Valdivielso P, Ramírez-Bollero J and Pérez-López C contributed to the paper.
Supported by Grant to Grupo CTS-159 of PAIDI (Plan Andaluz de Investigación, Desarrollo e Innovación) de la Junta de Andalucía
Correspondence to: Dr. Pedro Valdivielso, UGC de Medicina Interna, Hospital “Virgen de la Victoria” de Málaga y Departamento de Medicina y Dermatología, Universidad de Málaga, Campus de Teatinos s/n, 29010 Málaga, Spain. valdivielso@uma.es
Telephone: +34-951-032365 Fax: +34-952-131511
Received: January 24, 2014
Revised: March 19, 2014
Accepted: July 17, 2014
Published online: October 15, 2014
Processing time: 205 Days and 8.3 Hours
Revised: March 19, 2014
Accepted: July 17, 2014
Published online: October 15, 2014
Processing time: 205 Days and 8.3 Hours
Core Tip
Core tip: Peripheral arterial disease is highly prevalent in type 2 diabetes; traditional risk factors contribute to the disease. Interestingly, postprandial lipidaemia is increased in both conditions. However, one study showed that only subjects with both type 2 diabetes and peripheral arterial disease had elevation of postprandial lipids; subjects with type 2 diabetes and a normal ankle-brachial index had a normal postprandial response. Because most of the triglycerides of chylomicrons are extracted in muscle and adipose cells in the legs, the authors speculate on whether arteriosclerosis in the legs may contribute to greater postprandial lipidaemia.