Observational Study
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World J Diabetes. Aug 15, 2014; 5(4): 569-576
Published online Aug 15, 2014. doi: 10.4239/wjd.v5.i4.569
Fifteen-year follow-up of quality of life in type 1 diabetes mellitus
Peter R van Dijk, Susan JJ Logtenberg, Klaas H Groenier, Joost C Keers, Henk JG Bilo, Nanne Kleefstra
Peter R van Dijk, Susan JJ Logtenberg, Klaas H Groenier, Henk JG Bilo, Nanne Kleefstra, Diabetes Centre, Isala, 8000 GK Zwolle, The Netherlands
Susan JJ Logtenberg, Henk JG Bilo, Nanne Kleefstra, Department of Internal Medicine, University Medical Center Groningen, University of Groningen, 9712 CP Groningen, The Netherlands
Klaas H Groenier, Department of General Practice, University Medical Center Groningen, University of Groningen, 9712 CP Groningen, The Netherlands
Joost C Keers, Research Institute, Martini Hospital, 9728 NT Groningen, The Netherlands
Henk JG Bilo, Department of Internal Medicine, Isala, 8000 GK Zwolle, The Netherlands
Nanne Kleefstra, Langerhans Medical Research Group, 8000 GK Zwolle, The Netherlands
Author contributions: Keers JC, Bilo HJG and Kleefstra N designed the research; van Dijk PR and Logtenberg SJJ performed the research; van Dijk PR, Logtenberg SJJ and Groenier KH contributed to statistical analysis; van Dijk PR, Logtenberg SJJ, Groenier KH, Keers JC, Bilo HJG and Kleefstra N contributed to interpretation of data and writing of the paper.
Correspondence to: Peter R van Dijk, MD, Diabetes Center, Isala, PO Box 10400, 8000 GK Zwolle, The Netherlands. p.r.van.dijk@isala.nl
Telephone: +31-38-4247942 Fax: +31-38-4247695
Received: February 14, 2014
Revised: April 11, 2014
Accepted: May 16, 2014
Published online: August 15, 2014
Processing time: 174 Days and 22.4 Hours
Core Tip

Core tip: The results of this study demonstrate that over a period of 15 years, general health-related quality of life is almost stable among patients with type 1 diabetes mellitus. In addition, no differences with respect to metabolic control and general health-related quality of life were observed among type 1 diabetes mellitus patients treated with different insulin regimens (multiple daily injections or continuous subcutaneous insulin infusion).