Copyright
©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Diabetes. Aug 15, 2013; 4(4): 145-150
Published online Aug 15, 2013. doi: 10.4239/wjd.v4.i4.145
Published online Aug 15, 2013. doi: 10.4239/wjd.v4.i4.145
Diabetes-related impairment in bone strength is established early in the life course
Krista Casazza, Lynae J Hanks, Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294-3360, United States
Gregory A Clines, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-3360, United States
Hubert M Tse, Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-3360, United States
Alan W Eberhardt, Department of Biomedical Engineering, University of Alabama at Birmingham, Birmingham, AL 35294-3360, United States
Author contributions: Casazza K and Eberhardt AW performed the majority of experiments; Tse HM provided animals and analytical tools and were also involved in editing the manuscript; Casazza K, Clines GA, Hanks LJ and Tse HM coordinated and provided the collection of all data in addition to providing financial support for this work; Casazza K, Hanks LJ and Clines GA designed the study and wrote the manuscript.
Supported by R00DK083333 (KC); T32DK007545 (LJH); P60DK079626 UAB Diabetes Research Center Pilot/Feasibility Grant
Correspondence to: Krista Casazza, PhD, Department of Nutrition Sciences, University of Alabama at Birmingham, 1720 2nd Ave S, WEBB 439, Birmingham, AL 35294-3360, United States. kristac@uab.edu
Telephone: +1-205-9754316 Fax: +1-205-9347050
Received: March 6, 2013
Revised: April 24, 2013
Accepted: June 18, 2013
Published online: August 15, 2013
Processing time: 162 Days and 11.2 Hours
Revised: April 24, 2013
Accepted: June 18, 2013
Published online: August 15, 2013
Processing time: 162 Days and 11.2 Hours
Core Tip
Core tip: Diabetes-related impairment in bone microarchitectural properties and parameters of quality was apparent as early as 5 wk.