Gomez-Meade CA, Lopez-Mitnik G, Messiah SE, Arheart KL, Carrillo A, de la Cruz-Muñoz N. Cardiometabolic health among gastric bypass surgery patients with polycystic ovarian syndrome. World J Diabetes 2013; 4(3): 64-69 [PMID: 23772274 DOI: 10.4239/wjd.v4.i3.64]
Corresponding Author of This Article
Sarah E Messiah, PhD, MPH, Research Associate Professor, Division of Pediatric Clinical Research, Department of Pediatrics, University of Miami Miller School of Medicine, Batchelor Children’s Research Institute 541, 1580 NW 10th Avenue, Miami, FL 33130, United States. smessiah@med.miami.edu
Research Domain of This Article
Surgery
Article-Type of This Article
Brief Article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Jun 15, 2013; 4(3): 64-69 Published online Jun 15, 2013. doi: 10.4239/wjd.v4.i3.64
Cardiometabolic health among gastric bypass surgery patients with polycystic ovarian syndrome
Carley A Gomez-Meade, Gabriela Lopez-Mitnik, Sarah E Messiah, Kristopher L Arheart, Adriana Carrillo, Nestor de la Cruz-Muñoz
Carley A Gomez-Meade, Adriana Carrillo, Division of Pediatric Endocrinology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33130, United States
Gabriela Lopez-Mitnik, Sarah E Messiah, Division of Pediatric Clinical Research, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL 33130, United States
Kristopher L Arheart, Department of Epidemiology and Public Health Sciences, Division of Biostatistics, University of Miami Miller School of Medicine, Miami, FL 33130, United States
Nestor de la Cruz-Muñoz, Department of Surgery, University of Miami Miller School of Medicine, Miami, FL 33130, United States
Author contributions: Gomez-Meade CA, Messiah SE, Carrillo A and de la Cruz-Muñoz N conceived of the study design and acquisition of data; Lopez-Mitnik G and Arheart KL analyzed and interpreted the data; Messiah SE assisted in interpreting the data; all authors assisted with drafting and revising it critically for important intellectual content and as such gave final approval of the version to be published.
Correspondence to: Sarah E Messiah, PhD, MPH, Research Associate Professor, Division of Pediatric Clinical Research, Department of Pediatrics, University of Miami Miller School of Medicine, Batchelor Children’s Research Institute 541, 1580 NW 10th Avenue, Miami, FL 33130, United States. smessiah@med.miami.edu
Telephone: +1-305-2431943 Fax: +1-305-2438475
Received: January 7, 2013 Revised: April 23, 2013 Accepted: May 9, 2013 Published online: June 15, 2013 Processing time: 163 Days and 16.4 Hours
Core Tip
Core tip: Morbidly obese women with polycystic ovary syndrome (PCOS) who have undergone Roux-en-Y gastric bypass surgery show improvement in cardiometabolic disease risk at one year after the procedure. All women demonstrated a decrease in cardiometabolic disease risk factors including body mass index, glycated hemoglobin A1c (HgA1c), alanine aminotransferase (ALT), total cholesterol (TC), low-density lipoproteins (LDL) and triglyceride (TG). However, only Hispanic women showed a significant decreasing HgA1c and ALT, TC, LDL and TG one year after surgery. These ethnic group differences suggest there may be more comprehensive benefits in terms of cardiometabolic disease risk reduction after bariatric surgery in Hispanic women with PCOS vs other ethnic groups.
