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World J Diabetes. Apr 15, 2013; 4(2): 40-46
Published online Apr 15, 2013. doi: 10.4239/wjd.v4.i2.40
Published online Apr 15, 2013. doi: 10.4239/wjd.v4.i2.40
Parental transmission of type 2 diabetes mellitus in a highly endogamous population
Abdulbari Bener, Mohammad T Yousafzai, Department of Medical Statistics and Epidemiology, Hamad Medical Corporation, Doha 3050, Qatar
Abdulbari Bener, Department of Evidence for Population Health Unit, School of Epidemiology and Health Sciences, The University of Manchester, Manchester M13 9PP, United Kingdom
Abdulla OAA Al-Hamaq, Qatar Diabetic Association and Qatar Foundation, Doha 3050, Qatar
Abdul-Ghani Mohammad, Ralph A DeFronzo, Division of Diabetes, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Author contributions: Bener A designed this study and the data collection instrument and took care of the data analysis and preparation of the manuscript; Yousafzai MT, Al-Hamaq AOAA, Mohammad AG and DeFronzo RA were involved in the study design and data collection.
Supported by Qatar Diabetic Association and Qatar National Research Fund, QNRF UREP 07-099-3-023
Correspondence to: Abdulbari Bener, Professor, Advisor to WHO, Consultant and Head, Department of Medical Statistics and Epidemiology, Hamad Medical Corporation, Weill Cornell Medical College in Qatar, Doha 3050, Qatar. abener@hmc.org.qa
Telephone: +974-44393765 Fax: +974-44393769
Received: December 5, 2012
Revised: March 6, 2013
Accepted: March 15, 2013
Published online: April 15, 2013
Processing time: 131 Days and 6.5 Hours
Revised: March 6, 2013
Accepted: March 15, 2013
Published online: April 15, 2013
Processing time: 131 Days and 6.5 Hours
Core Tip
Core tip: Diabetes is a disease that has a strong clustering in families and has a genetic component. Family history is a well-known risk factor for developing of type 2 diabetes mellitus (T2DM). The present study found a significant maternal effect in transmission of T2DM. Family history is associated with the increased incidence of diabetes.