Ferroptosis: A novel therapeutic target for diabetic cardiomyopathy

doi:10.4239/wjd.v16.i6.104665

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 16, Issue 6

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (199)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-3) series, Tables (1-1) series.

Item

Count

PDF

HTML

Figures (1-3)

Tables (1-1)

Sum=191

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=1

Jun 15, 2025 (publication date) through Jun 16, 2025

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Diabetes

ISSN

1948-9358

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Diabetes. Jun 15, 2025; 16(6): 104665
Published online Jun 15, 2025. doi: 10.4239/wjd.v16.i6.104665

Ferroptosis: A novel therapeutic target for diabetic cardiomyopathy

Gui-Zhi Li, Jia-Yin Liu, Hong Zhou

Gui-Zhi Li, Hong Zhou, Department of Endocrinology, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China

Jia-Yin Liu, Department of Oncology, The Fourth Hospital of Hebei Medical University, Shijiazhuang 050011, Hebei Province, China

Co-first authors: Gui-Zhi Li and Jia-Yin Liu.

Author contributions: Li GZ and Liu JY contributed equally; Li GZ contributed to conceptualization, writing - original draft; Liu JY contributed to writing - review, resources, analysis; Zhou H modified the original manuscript; All authors have read and approved the final manuscript.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Hong Zhou, MD, Chief Physician, Professor, Department of Endocrinology, The Second Hospital of Hebei Medical University, No. 215 Heping West Road, Shijiazhuang 050000, Hebei Province, China. zhoubs2013@hebmu.edu.cn

Received: December 28, 2024
Revised: March 24, 2025
Accepted: May 7, 2025
Published online: June 15, 2025
Processing time: 168 Days and 9.8 Hours

Core Tip

Core Tip: Ferroptosis, a form of iron-dependent programmed cell death, plays a key role in the development of diabetic cardiomyopathy (DCM), contributing to oxidative stress, inflammation, and myocardial damage. Inhibiting ferroptosis can potentially alleviate DCM and prevent its progression to heart failure. This emerging pathway offers a promising therapeutic target for DCM, providing new hope for the management of DCM.